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  5. PSME_00014113-RA

PSME_00014113-RA


Description : (at5g58230 : 754.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1508.0) & (original description: no original description)


Gene families : OG_42_0002428 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002428_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00014113-RA
Cluster HCCA clusters: Cluster_146

Target Alias Description ECC score Gene Family Method Actions
At2g16780 No alias WD-40 repeat-containing protein MSI2... 0.02 Orthogroups_2024-Update
Bradi4g36580 No alias Transducin/WD40 repeat-like superfamily protein 0.03 Orthogroups_2024-Update
Brara.J01212.1 No alias component *(MSI1) of PRC2 histone methylation complex &... 0.05 Orthogroups_2024-Update
LOC_Os09g36900 No alias WD domain, G-beta repeat domain containing protein, expressed 0.06 Orthogroups_2024-Update
Seita.2G291200.1 No alias component *(CAF1c/MSI) of CAF1 histone chaperone complex... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0006352 DNA-templated transcription, initiation IEP Predicted GO
BP GO:0006357 regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016746 transferase activity, transferring acyl groups IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032784 regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032786 positive regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
BP GO:0034243 regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
CC GO:0043190 ATP-binding cassette (ABC) transporter complex IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044459 plasma membrane part IEP Predicted GO
BP GO:0045893 positive regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0045944 positive regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051254 positive regulation of RNA metabolic process IEP Predicted GO
CC GO:0098533 ATPase dependent transmembrane transport complex IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
CC GO:0098797 plasma membrane protein complex IEP Predicted GO
CC GO:1902495 transmembrane transporter complex IEP Predicted GO
BP GO:1902680 positive regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903508 positive regulation of nucleic acid-templated transcription IEP Predicted GO
CC GO:1904949 ATPase complex IEP Predicted GO
CC GO:1990351 transporter complex IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 371 406
IPR001680 WD40_repeat 224 260
IPR001680 WD40_repeat 313 350
IPR001680 WD40_repeat 268 306
IPR022052 Histone-bd_RBBP4_N 23 92
No external refs found!