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- PSME_00014572-RA
PSME_00014572-RA
Description : (p17569|nia_cucma : 1080.0) Nitrate reductase [NADH] (EC 1.7.1.1) (NR) - Cucurbita maxima (Pumpkin) (Winter squash) & (at1g77760 : 1037.0) Encodes the cytosolic minor isoform of nitrate reductase (NR). Involved in the first step of nitrate assimilation, it contributes about 15% of the nitrate reductase activity in shoots. Similar to molybdopterin oxidoreductases at the N-terminus, and to FAD/NAD-binding cytochrome reductases at the C-terminus. Cofactors: FAD, heme iron (cytochrome B-557), and molybdenum-pterin.; nitrate reductase 1 (NIA1); FUNCTIONS IN: nitrate reductase activity, protein binding; INVOLVED IN: nitric oxide biosynthetic process, nitrate assimilation, response to light stimulus; LOCATED IN: cytosol; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Nitrate reductase NADH dependent (InterPro:IPR012137), Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Oxidoreductase, FAD-binding domain (InterPro:IPR008333), Immunoglobulin E-set (InterPro:IPR014756), Cytochrome b5 (InterPro:IPR001199), NADH:cytochrome b5 reductase (CBR) (InterPro:IPR001834), Oxidoreductase, molybdopterin-binding domain (InterPro:IPR000572), Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Oxidoreductase, molybdopterin binding site (InterPro:IPR022407), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Eukaryotic molybdopterin oxidoreductase (InterPro:IPR008335), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709), Moybdenum cofactor oxidoreductase, dimerisation (InterPro:IPR005066); BEST Arabidopsis thaliana protein match is: nitrate reductase 2 (TAIR:AT1G37130.1); Has 14813 Blast hits to 14437 proteins in 2198 species: Archae - 168; Bacteria - 6976; Metazoa - 1728; Fungi - 2215; Plants - 1479; Viruses - 3; Other Eukaryotes - 2244 (source: NCBI BLink). & (reliability: 2074.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00014572-RA | |
Cluster | HCCA clusters: Cluster_103 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
LOC_Os08g36500 | No alias | nitrate reductase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0003824 | catalytic activity | None | Extended |
MF | GO:0005488 | binding | None | Extended |
BP | GO:0006082 | organic acid metabolic process | None | Extended |
BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
BP | GO:0008150 | biological_process | None | Extended |
BP | GO:0008152 | metabolic process | None | Extended |
BP | GO:0009987 | cellular process | None | Extended |
MF | GO:0016491 | oxidoreductase activity | IEA | InterProScan predictions |
MF | GO:0030151 | molybdenum ion binding | IEA | InterProScan predictions |
BP | GO:0042126 | nitrate metabolic process | None | Extended |
BP | GO:0042128 | nitrate assimilation | IEA | InterProScan predictions |
MF | GO:0043167 | ion binding | None | Extended |
MF | GO:0043169 | cation binding | None | Extended |
BP | GO:0043436 | oxoacid metabolic process | None | Extended |
BP | GO:0044237 | cellular metabolic process | None | Extended |
BP | GO:0044281 | small molecule metabolic process | None | Extended |
MF | GO:0046872 | metal ion binding | None | Extended |
MF | GO:0046914 | transition metal ion binding | None | Extended |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
BP | GO:0071704 | organic substance metabolic process | None | Extended |
BP | GO:0071941 | nitrogen cycle metabolic process | None | Extended |
BP | GO:2001057 | reactive nitrogen species metabolic process | None | Extended |
Type | GO Term | Name | Evidence | Source |
MF | GO:0008168 | methyltransferase activity | IEP | Predicted GO |
MF | GO:0016741 | transferase activity, transferring one-carbon groups | IEP | Predicted GO |
MF | GO:0046983 | protein dimerization activity | IEP | Predicted GO |
MF | GO:0051087 | chaperone binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR001433 | OxRdtase_FAD/NAD-bd | 778 | 885 |
IPR000572 | OxRdtase_Mopterin-bd_dom | 120 | 296 |
IPR001199 | Cyt_B5-like_heme/steroid-bd | 515 | 587 |
IPR008333 | Cbr1-like_FAD-bd_dom | 651 | 758 |
IPR005066 | MoCF_OxRdtse_dimer | 326 | 456 |