PSME_00014793-RA


Description : (at1g11310 : 486.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (o49914|mloh1_orysa : 468.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (reliability: 972.0) & (original description: no original description)


Gene families : OG_42_0000124 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000124_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00014793-RA

Target Alias Description ECC score Gene Family Method Actions
At1g61560 No alias MLO-like protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q94KB7] 0.03 Orthogroups_2024-Update
Brara.D02377.1 No alias disease resistance mediator *(MLO2/6/12) of Systemic... 0.04 Orthogroups_2024-Update
Glyma.01G165200 No alias Seven transmembrane MLO family protein 0.04 Orthogroups_2024-Update
Glyma.08G188600 No alias Seven transmembrane MLO family protein 0.06 Orthogroups_2024-Update
HORVU0Hr1G008830.1 No alias Unknown function 0.05 Orthogroups_2024-Update
MA_20495g0020 No alias no hits & (original description: no original description) 0.03 Orthogroups_2024-Update
Sopen06g034180 No alias Mlo family 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006952 defense response IEA InterProScan predictions
CC GO:0016021 integral component of membrane IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0006855 drug transmembrane transport IEP Predicted GO
MF GO:0008173 RNA methyltransferase activity IEP Predicted GO
MF GO:0015238 drug transmembrane transporter activity IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
InterPro domains Description Start Stop
IPR004326 Mlo 10 508
No external refs found!