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- Pseudotsuga menziesii
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- PSME_00014793-RA
PSME_00014793-RA
Description : (at1g11310 : 486.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (o49914|mloh1_orysa : 468.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (reliability: 972.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00014793-RA | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
At1g61560 | No alias | MLO-like protein 6 [Source:UniProtKB/Swiss-Prot;Acc:Q94KB7] | 0.03 | Orthogroups_2024-Update | |
Brara.D02377.1 | No alias | disease resistance mediator *(MLO2/6/12) of Systemic... | 0.04 | Orthogroups_2024-Update | |
Glyma.01G165200 | No alias | Seven transmembrane MLO family protein | 0.04 | Orthogroups_2024-Update | |
Glyma.08G188600 | No alias | Seven transmembrane MLO family protein | 0.06 | Orthogroups_2024-Update | |
HORVU0Hr1G008830.1 | No alias | Unknown function | 0.05 | Orthogroups_2024-Update | |
MA_20495g0020 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
Sopen06g034180 | No alias | Mlo family | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
CC | GO:0005575 | cellular_component | None | Extended |
BP | GO:0006950 | response to stress | None | Extended |
BP | GO:0006952 | defense response | IEA | InterProScan predictions |
BP | GO:0008150 | biological_process | None | Extended |
CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
CC | GO:0031224 | intrinsic component of membrane | None | Extended |
CC | GO:0044425 | membrane part | None | Extended |
BP | GO:0050896 | response to stimulus | None | Extended |
Type | GO Term | Name | Evidence | Source |
BP | GO:0006855 | drug transmembrane transport | IEP | Predicted GO |
MF | GO:0008173 | RNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0015238 | drug transmembrane transporter activity | IEP | Predicted GO |
BP | GO:0015893 | drug transport | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR004326 | Mlo | 10 | 508 |