Description : (p49358|glyn_flapr : 512.0) Serine hydroxymethyltransferase 2, mitochondrial precursor (EC 2.1.2.1) (Serine methylase) (Glycine hydroxymethyltransferase) (SHMT) - Flaveria pringlei & (at5g26780 : 507.0) Encodes a protein with serine hydroxymethyltransferase activity which is thought to be localized in the mitochondrial matrix. SHM2 expression fails to rescue the conditional lethal phenotype of the shm1-1 mutant, defective in SHM1.; serine hydroxymethyltransferase 2 (SHM2); FUNCTIONS IN: glycine hydroxymethyltransferase activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine transhydroxymethyltransferase 1 (TAIR:AT4G37930.1); Has 11562 Blast hits to 11539 proteins in 2821 species: Archae - 258; Bacteria - 6362; Metazoa - 333; Fungi - 287; Plants - 321; Viruses - 6; Other Eukaryotes - 3995 (source: NCBI BLink). & (reliability: 1014.0) & (original description: no original description)
Gene families : OG_42_0000626 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000626_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00015002-RA | |
Cluster | HCCA clusters: Cluster_246 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.H01745.1 | No alias | serine hydroxymethyltransferase & EC_2.1 transferase... | 0.03 | Orthogroups_2024-Update | |
Glyma.18G150000 | No alias | serine transhydroxymethyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
Seita.5G398800.1 | No alias | serine hydroxymethyltransferase *(SHM) & serine... | 0.03 | Orthogroups_2024-Update | |
Solyc02g091560 | No alias | Serine hydroxymethyltransferase (AHRD V3.3 *** A0A0R4J3Y9_SOYBN) | 0.06 | Orthogroups_2024-Update | |
Sopen02g036190 | No alias | Serine hydroxymethyltransferase | 0.04 | Orthogroups_2024-Update | |
evm.model.contig_2050.3 | No alias | (at5g26780 : 637.0) Encodes a protein with serine... | 0.02 | Orthogroups_2024-Update | |
evm.model.tig00001130.31 | No alias | (at4g13930 : 555.0) Encodes a serine... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
MF | GO:0004425 | indole-3-glycerol-phosphate synthase activity | IEP | Predicted GO |
MF | GO:0004655 | porphobilinogen synthase activity | IEP | Predicted GO |
BP | GO:0006284 | base-excision repair | IEP | Predicted GO |
MF | GO:0008237 | metallopeptidase activity | IEP | Predicted GO |
MF | GO:0009975 | cyclase activity | IEP | Predicted GO |
MF | GO:0009976 | tocopherol cyclase activity | IEP | Predicted GO |
MF | GO:0016836 | hydro-lyase activity | IEP | Predicted GO |
BP | GO:0033013 | tetrapyrrole metabolic process | IEP | Predicted GO |
BP | GO:0033014 | tetrapyrrole biosynthetic process | IEP | Predicted GO |
MF | GO:0070569 | uridylyltransferase activity | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR039429 | SHMT-like_dom | 2 | 241 |
No external refs found! |