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  5. PSME_00015569-RA

PSME_00015569-RA


Description : (o24146|4cl2_tobac : 689.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Nicotiana tabacum (Common tobacco) & (at3g21240 : 644.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, ferulic acid, 5-OH-ferulic acid and cinnamic acid. At4CL2 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 2 (4CL2); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 1 (TAIR:AT1G51680.1); Has 86092 Blast hits to 78635 proteins in 3758 species: Archae - 1209; Bacteria - 54193; Metazoa - 3597; Fungi - 4717; Plants - 2816; Viruses - 1; Other Eukaryotes - 19559 (source: NCBI BLink). & (reliability: 1288.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00015569-RA
Cluster HCCA clusters: Cluster_217

Target Alias Description ECC score Gene Family Method Actions
143817 No alias OPC-8:0 CoA ligase1 0.03 Orthogroups_2024-Update
171251 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
173133 No alias 4-coumarate:CoA ligase 3 0.02 Orthogroups_2024-Update
A4A49_10638 No alias 4-coumarate--coa ligase 2 0.05 Orthogroups_2024-Update
A4A49_31911 No alias 4-coumarate--coa ligase-like 6 0.03 Orthogroups_2024-Update
A4A49_40482 No alias 4-coumarate--coa ligase 1 0.03 Orthogroups_2024-Update
A4A49_41306 No alias 4-coumarate--coa ligase 2 0.03 Orthogroups_2024-Update
At1g20490 No alias AMP-dependent synthetase and ligase family protein... 0.02 Orthogroups_2024-Update
At1g20510 No alias 4-coumarate--CoA ligase-like 5... 0.03 Orthogroups_2024-Update
At1g62940 No alias 4-coumarate--CoA ligase-like 1... 0.02 Orthogroups_2024-Update
At1g65060 No alias 4-coumarate--CoA ligase 3... 0.03 Orthogroups_2024-Update
At3g21230 No alias 4-coumarate--CoA ligase 4... 0.02 Orthogroups_2024-Update
Bradi3g05750 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Bradi3g37300 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Bradi3g52350 No alias 4-coumarate:CoA ligase 3 0.06 Orthogroups_2024-Update
Bradi5g04760 No alias acyl-CoA synthetase 5 0.05 Orthogroups_2024-Update
Brara.F01460.1 No alias OPC-8 0.03 Orthogroups_2024-Update
Brara.H02326.1 No alias OPC-8 0.03 Orthogroups_2024-Update
Glyma.01G232400 No alias 4-coumarate:CoA ligase 3 0.03 Orthogroups_2024-Update
Glyma.04G194200 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Glyma.06G171900 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Glyma.11G010500 No alias 4-coumarate:CoA ligase 3 0.02 Orthogroups_2024-Update
Glyma.13G372000 No alias 4-coumarate:CoA ligase 2 0.06 Orthogroups_2024-Update
Glyma.18G076900 No alias acyl-CoA synthetase 5 0.03 Orthogroups_2024-Update
HORVU0Hr1G002720.3 No alias Unknown function 0.02 Orthogroups_2024-Update
HORVU6Hr1G030390.2 No alias p-coumarate 0.03 Orthogroups_2024-Update
LOC_Os03g04000 No alias AMP-binding domain containing protein, expressed 0.03 Orthogroups_2024-Update
MA_10430515g0010 No alias (at1g20510 : 564.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.05 Orthogroups_2024-Update
MA_10432138g0010 No alias (at1g20510 : 477.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
MA_109119g0010 No alias (p31687|4cl2_soybn : 667.0) 4-coumarate--CoA ligase 2... 0.06 Orthogroups_2024-Update
MA_4881g0010 No alias (at1g20510 : 253.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
MA_56692g0010 No alias (o24146|4cl2_tobac : 616.0) 4-coumarate--CoA ligase 2... 0.03 Orthogroups_2024-Update
Mp1g27780.1 No alias 4-coumarate--CoA ligase-like 7 OS=Arabidopsis thaliana... 0.04 Orthogroups_2024-Update
Mp5g01200.1 No alias p-coumarate:CoA ligase. 4-coumarate:CoA ligase (4CL) 0.03 Orthogroups_2024-Update
PSME_00017730-RA No alias (at1g20510 : 538.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
Potri.001G036900 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Potri.017G035100 No alias OPC-8:0 CoA ligase1 0.02 Orthogroups_2024-Update
Potri.018G094200 No alias 4-coumarate:CoA ligase 2 0.05 Orthogroups_2024-Update
Pp1s12_59V6 No alias amp dependent 0.03 Orthogroups_2024-Update
Pp1s20_346V6 No alias 4-coumarate: ligase 0.02 Orthogroups_2024-Update
Pp1s71_170V6 No alias 4-coumarate: ligase 0.05 Orthogroups_2024-Update
Seita.1G065800.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Seita.1G283300.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Seita.4G191500.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Seita.6G167900.1 No alias p-coumarate 0.02 Orthogroups_2024-Update
Seita.9G552000.1 No alias OPC-8 0.03 Orthogroups_2024-Update
Sobic.001G187000.2 No alias Unknown function 0.03 Orthogroups_2024-Update
Sobic.001G516600.1 No alias OPC-8 0.04 Orthogroups_2024-Update
Sobic.007G089900.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Solyc03g111170 No alias 4-coumarate:CoA ligase-like protein (AHRD V3.3 *** G7J515_MEDTR) 0.03 Orthogroups_2024-Update
Solyc03g117870 No alias 4-coumarate--CoA ligase 0.03 Orthogroups_2024-Update
Solyc07g008360 No alias ribosomal protein L30/L7 family protein 0.03 Orthogroups_2024-Update
Sopen03g001090 No alias AMP-binding enzyme 0.02 Orthogroups_2024-Update
Sopen03g027780 No alias AMP-binding enzyme 0.02 Orthogroups_2024-Update
Sopen12g031420 No alias AMP-binding enzyme 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
MF GO:0003700 DNA-binding transcription factor activity IEP Predicted GO
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Predicted GO
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003989 acetyl-CoA carboxylase activity IEP Predicted GO
MF GO:0004107 chorismate synthase activity IEP Predicted GO
MF GO:0004470 malic enzyme activity IEP Predicted GO
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Predicted GO
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006536 glutamate metabolic process IEP Predicted GO
BP GO:0006537 glutamate biosynthetic process IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
MF GO:0008198 ferrous iron binding IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009066 aspartate family amino acid metabolic process IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009072 aromatic amino acid family metabolic process IEP Predicted GO
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009690 cytokinin metabolic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010817 regulation of hormone levels IEP Predicted GO
MF GO:0015930 glutamate synthase activity IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016421 CoA carboxylase activity IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016615 malate dehydrogenase activity IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen IEP Predicted GO
MF GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016885 ligase activity, forming carbon-carbon bonds IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
MF GO:0019139 cytokinin dehydrogenase activity IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0034754 cellular hormone metabolic process IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042445 hormone metabolic process IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043648 dicarboxylic acid metabolic process IEP Predicted GO
BP GO:0043650 dicarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
MF GO:0046872 metal ion binding IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
MF GO:0051213 dioxygenase activity IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901607 alpha-amino acid biosynthetic process IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR025110 AMP-bd_C 481 554
IPR000873 AMP-dep_Synth/Lig 63 472
No external refs found!