PSME_00015673-RA


Description : (at1g11310 : 477.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (o49873|mloh1_horvu : 430.0) MLO protein homolog 1 - Hordeum vulgare (Barley) & (reliability: 954.0) & (original description: no original description)


Gene families : OG_42_0000124 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000124_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00015673-RA

Target Alias Description ECC score Gene Family Method Actions
97970 No alias Seven transmembrane MLO family protein 0.04 Orthogroups_2024-Update
Brara.K00750.1 No alias Unknown function 0.03 Orthogroups_2024-Update
GRMZM2G000376 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
Glyma.02G063900 No alias Seven transmembrane MLO family protein 0.03 Orthogroups_2024-Update
Glyma.13G234400 No alias Seven transmembrane MLO family protein 0.04 Orthogroups_2024-Update
HORVU2Hr1G118780.6 No alias Unknown function 0.03 Orthogroups_2024-Update
MA_10435934g0010 No alias (at1g61560 : 446.0) A member of a large family of... 0.02 Orthogroups_2024-Update
MA_321559g0010 No alias (o49914|mloh1_orysa : 163.0) MLO protein homolog 1... 0.03 Orthogroups_2024-Update
PSME_00026865-RA No alias (o49914|mloh1_orysa : 126.0) MLO protein homolog 1... 0.03 Orthogroups_2024-Update
PSME_00034784-RA No alias (at1g61560 : 355.0) A member of a large family of... 0.05 Orthogroups_2024-Update
Pp1s60_220V6 No alias calmodulin binding 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006952 defense response IEA InterProScan predictions
CC GO:0016021 integral component of membrane IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003968 RNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0003993 acid phosphatase activity IEP Predicted GO
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016791 phosphatase activity IEP Predicted GO
MF GO:0016851 magnesium chelatase activity IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0042578 phosphoric ester hydrolase activity IEP Predicted GO
MF GO:0051002 ligase activity, forming nitrogen-metal bonds IEP Predicted GO
MF GO:0051003 ligase activity, forming nitrogen-metal bonds, forming coordination complexes IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR004326 Mlo 466 561
IPR004326 Mlo 10 436
No external refs found!