PSME_00016183-RA


Description : (at3g22590 : 186.0) Encodes PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP), a homolog of human Paf1 Complex (Paf1C) subunit Parafibromin. Human Parafibromin assists in mediating output from the Wnt signaling pathway, and dysfunction of the encoding gene HRPT2 conditions specific cancer-related disease phenotypes. PHP resides in a ~670-kDa protein complex in nuclear extracts, and physically interacts with other known Paf1C-related proteins in vivo. Loss of PHP specifically conditioned accelerated phase transition from vegetative growth to flowering and resulted in misregulation of a very limited subset of genes that included the flowering repressor FLOWERING LOCUS C (FLC).; PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP); CONTAINS InterPro DOMAIN/s: RNA polymerase II accessory factor, Cdc73 (InterPro:IPR007852); Has 502 Blast hits to 395 proteins in 198 species: Archae - 0; Bacteria - 0; Metazoa - 257; Fungi - 127; Plants - 42; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink). & (reliability: 372.0) & (original description: no original description)


Gene families : OG_42_0003860 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003860_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00016183-RA
Cluster HCCA clusters: Cluster_137

Target Alias Description ECC score Gene Family Method Actions
Cre02.g104550 No alias PLANT HOMOLOGOUS TO PARAFIBROMIN 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR031336 CDC73_C 175 277
No external refs found!