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Description : (o23787|thi4_citsi : 513.0) Thiazole biosynthetic enzyme, chloroplast precursor - Citrus sinensis (Sweet orange) & (at5g54770 : 497.0) Encodes a thiamine biosynthetic gene that has a dual function in thiamine biosynthesis and mitochondrial DNA damage tolerance. It appears to be involved in producing the thiazole portion of thiamine (vitamin B1). A crystal structure of the protein reveals that it forms a 2-ring homo-octamer.; THI1; FUNCTIONS IN: protein homodimerization activity, zinc ion binding; INVOLVED IN: oxazole or thiazole biosynthetic process, response to cold, thiamin biosynthetic process, response to DNA damage stimulus; LOCATED IN: in 6 components; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thiamine biosynthesis Thi4 protein (InterPro:IPR002922); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 994.0) & (original description: no original description)
Gene families : OG_42_0004114 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004114_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00016249-RA | |
| Cluster | HCCA clusters: Cluster_120 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0000413 | protein peptidyl-prolyl isomerization | IEP | Predicted GO |
| MF | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | IEP | Predicted GO |
| MF | GO:0004222 | metalloendopeptidase activity | IEP | Predicted GO |
| MF | GO:0004332 | fructose-bisphosphate aldolase activity | IEP | Predicted GO |
| MF | GO:0004664 | prephenate dehydratase activity | IEP | Predicted GO |
| BP | GO:0006558 | L-phenylalanine metabolic process | IEP | Predicted GO |
| MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
| MF | GO:0008237 | metallopeptidase activity | IEP | Predicted GO |
| BP | GO:0009072 | aromatic amino acid family metabolic process | IEP | Predicted GO |
| BP | GO:0009073 | aromatic amino acid family biosynthetic process | IEP | Predicted GO |
| BP | GO:0009094 | L-phenylalanine biosynthetic process | IEP | Predicted GO |
| BP | GO:0009095 | aromatic amino acid family biosynthetic process, prephenate pathway | IEP | Predicted GO |
| CC | GO:0009521 | photosystem | IEP | Predicted GO |
| CC | GO:0009522 | photosystem I | IEP | Predicted GO |
| CC | GO:0009538 | photosystem I reaction center | IEP | Predicted GO |
| CC | GO:0009654 | photosystem II oxygen evolving complex | IEP | Predicted GO |
| BP | GO:0010109 | regulation of photosynthesis | IEP | Predicted GO |
| BP | GO:0010207 | photosystem II assembly | IEP | Predicted GO |
| MF | GO:0010242 | oxygen evolving activity | IEP | Predicted GO |
| BP | GO:0015979 | photosynthesis | IEP | Predicted GO |
| BP | GO:0016053 | organic acid biosynthetic process | IEP | Predicted GO |
| MF | GO:0016829 | lyase activity | IEP | Predicted GO |
| MF | GO:0016832 | aldehyde-lyase activity | IEP | Predicted GO |
| MF | GO:0016836 | hydro-lyase activity | IEP | Predicted GO |
| MF | GO:0016859 | cis-trans isomerase activity | IEP | Predicted GO |
| BP | GO:0017144 | drug metabolic process | IEP | Predicted GO |
| BP | GO:0018193 | peptidyl-amino acid modification | IEP | Predicted GO |
| BP | GO:0018208 | peptidyl-proline modification | IEP | Predicted GO |
| MF | GO:0019208 | phosphatase regulator activity | IEP | Predicted GO |
| MF | GO:0019211 | phosphatase activator activity | IEP | Predicted GO |
| BP | GO:0019438 | aromatic compound biosynthetic process | IEP | Predicted GO |
| BP | GO:0034622 | cellular protein-containing complex assembly | IEP | Predicted GO |
| BP | GO:0042548 | regulation of photosynthesis, light reaction | IEP | Predicted GO |
| BP | GO:0042549 | photosystem II stabilization | IEP | Predicted GO |
| BP | GO:0043467 | regulation of generation of precursor metabolites and energy | IEP | Predicted GO |
| BP | GO:0043933 | protein-containing complex subunit organization | IEP | Predicted GO |
| BP | GO:0044283 | small molecule biosynthetic process | IEP | Predicted GO |
| CC | GO:0044436 | thylakoid part | IEP | Predicted GO |
| BP | GO:0046394 | carboxylic acid biosynthetic process | IEP | Predicted GO |
| MF | GO:0051287 | NAD binding | IEP | Predicted GO |
| BP | GO:0065003 | protein-containing complex assembly | IEP | Predicted GO |
| CC | GO:0098796 | membrane protein complex | IEP | Predicted GO |
| BP | GO:1901362 | organic cyclic compound biosynthetic process | IEP | Predicted GO |
| BP | GO:1902221 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | IEP | Predicted GO |
| BP | GO:1902223 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process | IEP | Predicted GO |
| CC | GO:1990204 | oxidoreductase complex | IEP | Predicted GO |
No InterPro domains available for this sequence
| No external refs found! |