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  5. PSME_00016707-RA

PSME_00016707-RA


Description : (p31251|ube12_wheat : 1493.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at2g30110 : 1473.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (reliability: 2946.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00016707-RA
Cluster HCCA clusters: Cluster_126

Target Alias Description ECC score Gene Family Method Actions
Cre09.g386400 No alias ubiquitin activating enzyme 2 0.05 Orthogroups_2024-Update
Glyma.02G229700 No alias ubiquitin activating enzyme 2 0.04 Orthogroups_2024-Update
Glyma.11G166100 No alias ubiquitin-activating enzyme 1 0.07 Orthogroups_2024-Update
Kfl00008_0090 kfl00008_0090_v1.1 (p31251|ube12_wheat : 1361.0) Ubiquitin-activating... 0.03 Orthogroups_2024-Update
MA_107903g0010 No alias (p31251|ube12_wheat : 1518.0) Ubiquitin-activating... 0.07 Orthogroups_2024-Update
Mp4g15300.1 No alias ubiquitin-activating E1 protein 0.02 Orthogroups_2024-Update
Mp7g08080.1 No alias ubiquitin-activating E1 protein 0.02 Orthogroups_2024-Update
Seita.7G331900.1 No alias E1 ubiquitin-activating enzyme 0.05 Orthogroups_2024-Update
Seita.8G019500.1 No alias E1 ubiquitin-activating enzyme 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003968 RNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004019 adenylosuccinate synthase activity IEP Predicted GO
MF GO:0004512 inositol-3-phosphate synthase activity IEP Predicted GO
MF GO:0004559 alpha-mannosidase activity IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005086 ARF guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
BP GO:0006013 mannose metabolic process IEP Predicted GO
BP GO:0006020 inositol metabolic process IEP Predicted GO
BP GO:0006021 inositol biosynthetic process IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006357 regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0006367 transcription initiation from RNA polymerase II promoter IEP Predicted GO
BP GO:0006397 mRNA processing IEP Predicted GO
BP GO:0006487 protein N-linked glycosylation IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0006891 intra-Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008134 transcription factor binding IEP Predicted GO
CC GO:0008250 oligosaccharyltransferase complex IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0015923 mannosidase activity IEP Predicted GO
BP GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient IEP Predicted GO
BP GO:0015991 ATP hydrolysis coupled proton transport IEP Predicted GO
BP GO:0016071 mRNA metabolic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016872 intramolecular lyase activity IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
MF GO:0017069 snRNA binding IEP Predicted GO
MF GO:0017070 U6 snRNA binding IEP Predicted GO
CC GO:0017119 Golgi transport complex IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
CC GO:0030131 clathrin adaptor complex IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
MF GO:0030623 U5 snRNA binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032012 regulation of ARF protein signal transduction IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0032784 regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032786 positive regulation of DNA-templated transcription, elongation IEP Predicted GO
BP GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
CC GO:0033179 proton-transporting V-type ATPase, V0 domain IEP Predicted GO
BP GO:0034243 regulation of transcription elongation from RNA polymerase II promoter IEP Predicted GO
MF GO:0035091 phosphatidylinositol binding IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0045893 positive regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0045944 positive regulation of transcription by RNA polymerase II IEP Predicted GO
BP GO:0046165 alcohol biosynthetic process IEP Predicted GO
BP GO:0046173 polyol biosynthetic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046578 regulation of Ras protein signal transduction IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051056 regulation of small GTPase mediated signal transduction IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051254 positive regulation of RNA metabolic process IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090662 ATP hydrolysis coupled transmembrane transport IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
CC GO:0099023 tethering complex IEP Predicted GO
BP GO:0099131 ATP hydrolysis coupled ion transmembrane transport IEP Predicted GO
BP GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Predicted GO
BP GO:1902531 regulation of intracellular signal transduction IEP Predicted GO
BP GO:1902600 proton transmembrane transport IEP Predicted GO
BP GO:1902680 positive regulation of RNA biosynthetic process IEP Predicted GO
BP GO:1903508 positive regulation of nucleic acid-templated transcription IEP Predicted GO
InterPro domains Description Start Stop
IPR019572 UBA_E1_Cys 641 894
IPR000594 ThiF_NAD_FAD-bd 57 440
IPR018965 Ub-activating_enz_E1_C 964 1053
IPR032420 E1_4HB 302 371
IPR000594 ThiF_NAD_FAD-bd 454 952
IPR032418 E1_FCCH 230 301
No external refs found!