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  5. PSME_00018750-RA

PSME_00018750-RA


Description : (at3g55360 : 473.0) Enoyl-CoA reductase is involved in all very long chain fatty acids (VLCFA) elongation reactions that are required for cuticular wax, storage lipid and sphingolipid metabolism. The protein is located in the ER, but in contrast to its yeast homolog TSC13 is not particularly enriched in the nuclear envelope-vacuole junction. Mutants in this gene show abnormal organ morphology and stem glossiness. Cells in all tissues are only about 1/3 of the size of wild type cells. The morphological changes are most likely to result from the reduction in the VLCFA content of sphingolipids. Mutants also show abnormalities in the endocytic membrane organization and transport.; ECERIFERUM 10 (CER10); FUNCTIONS IN: fatty acid elongase activity, trans-2-enoyl-CoA reductase (NADPH) activity, 3-oxo-5-alpha-steroid 4-dehydrogenase activity; INVOLVED IN: sphingolipid metabolic process, wax biosynthetic process; LOCATED IN: endoplasmic reticulum, fatty acid elongase complex, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT5G16010.1); Has 1087 Blast hits to 1087 proteins in 269 species: Archae - 0; Bacteria - 73; Metazoa - 353; Fungi - 144; Plants - 184; Viruses - 0; Other Eukaryotes - 333 (source: NCBI BLink). & (reliability: 946.0) & (original description: no original description)


Gene families : OG_42_0006976 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006976_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00018750-RA
Cluster HCCA clusters: Cluster_181


Type GO Term Name Evidence Source
BP GO:0006629 lipid metabolic process IEA InterProScan predictions
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Predicted GO
BP GO:0008610 lipid biosynthetic process IEP Predicted GO
BP GO:0008654 phospholipid biosynthetic process IEP Predicted GO
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Predicted GO
MF GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor IEP Predicted GO
MF GO:0016780 phosphotransferase activity, for other substituted phosphate groups IEP Predicted GO
MF GO:0016846 carbon-sulfur lyase activity IEP Predicted GO
CC GO:0031225 anchored component of membrane IEP Predicted GO
CC GO:0031226 intrinsic component of plasma membrane IEP Predicted GO
BP GO:0044255 cellular lipid metabolic process IEP Predicted GO
CC GO:0046658 anchored component of plasma membrane IEP Predicted GO
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR001104 3-oxo-5_a-steroid_4-DH_C 157 307
No external refs found!