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PSME_00020111-RA


Description : (at1g78870 : 239.0) UBC35/UBC13A encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UBC35/UBC13A can form diubiquitin and triubiquitin chains in combination with MMZ1,2,3,4/(UEV1A,B,C,D) in vitro. It can also functionally complement an mms2 ubc13 mutation in budding yeast by increasing the double mutant's viability in the presence of the DNA damaging agent MMS, when it is co-expressed with MMZ / UEV1 genes. A wild type phenotype is restored with MMZ3/UEV1C and MMZ4/UEV1D, but only partial complementation is achieved with MMZ1/UEV1A or MMZ2/UEV1B.; ubiquitin-conjugating enzyme 35 (UBC35); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: root epidermal cell differentiation, response to cadmium ion, postreplication repair, response to iron ion, ubiquitin-dependent protein catabolic process; LOCATED IN: UBC13-MMS2 complex; EXPRESSED IN: male gametophyte, cultured cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 36 (TAIR:AT1G16890.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (p35130|ubc2_medsa : 114.0) Ubiquitin-conjugating enzyme E2-17 kDa (EC 6.3.2.19) (Ubiquitin-protein ligase) (Ubiquitin carrier protein) - Medicago sativa (Alfalfa) & (reliability: 478.0) & (original description: no original description)


Gene families : OG_42_0002519 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002519_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Pseudotsuga release: PSME_00020111-RA
Cluster HCCA clusters: Cluster_233

Target Alias Description ECC score Gene Family Method Actions
Bradi4g27897 No alias ubiquitin-conjugating enzyme 36 0.03 Orthogroups_2024-Update
Mp7g05230.1 No alias ubiquitin-conjugating E2 protein 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
BP GO:0000272 polysaccharide catabolic process IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003725 double-stranded RNA binding IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004807 triose-phosphate isomerase activity IEP Predicted GO
MF GO:0004843 thiol-dependent ubiquitin-specific protease activity IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Predicted GO
BP GO:0015986 ATP synthesis coupled proton transport IEP Predicted GO
MF GO:0016160 amylase activity IEP Predicted GO
MF GO:0016161 beta-amylase activity IEP Predicted GO
MF GO:0016860 intramolecular oxidoreductase activity IEP Predicted GO
MF GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
MF GO:0019829 cation-transporting ATPase activity IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
MF GO:0022853 active ion transmembrane transporter activity IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
MF GO:0042625 ATPase coupled ion transmembrane transporter activity IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
MF GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism IEP Predicted GO
MF GO:0046933 proton-transporting ATP synthase activity, rotational mechanism IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000608 UBQ-conjugat_E2 8 128
No external refs found!