PSME_00020187-RA

Description : (q8w1l6|mfp_orysa : 588.0) Peroxisomal fatty acid beta-oxidation multifunctional protein (MFP) [Includes: Enoyl-CoA hydratase (EC 4.2.1.17); 3-2-trans-enoyl-CoA isomerase (EC 5.3.3.8); 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (E & (at4g29010 : 578.0) Functions in beta-oxidation of fatty acids, similar to CuMFP with L-3-hydroxyacyl-CoA hydrolyase , L-3-hydroxyacyl-dehydrogenase, D-3-hydroxyacyl-CoA epimerase, and 3, 2-enoyl-CoA isomerase activities; ABNORMAL INFLORESCENCE MERISTEM (AIM1); FUNCTIONS IN: enoyl-CoA hydratase activity; INVOLVED IN: multicellular organismal development, flower development, fatty acid beta-oxidation, seed germination; LOCATED IN: cell wall, peroxisome, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Enoyl-CoA hydratase/isomerase, conserved site (InterPro:IPR018376), 3-hydroxyacyl-CoA dehydrogenase, conserved site (InterPro:IPR006180), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyacyl-CoA dehydrogenase, NAD binding (InterPro:IPR006176), Crotonase, core (InterPro:IPR001753), 3-hydroxyacyl-CoA dehydrogenase, C-terminal (InterPro:IPR006108); BEST Arabidopsis thaliana protein match is: multifunctional protein 2 (TAIR:AT3G06860.1); Has 47636 Blast hits to 46241 proteins in 2477 species: Archae - 813; Bacteria - 30277; Metazoa - 2018; Fungi - 1063; Plants - 649; Viruses - 0; Other Eukaryotes - 12816 (source: NCBI BLink). & (reliability: 1156.0) & (original description: no original description)

Gene families : OG_42_0001149 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001149_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00020187-RA
Cluster	HCCA clusters: Cluster_188

Target	Alias	Description	ECC score	Gene Family Method
Brara.A00825.1	No alias	multifunctional enzyme *(MFP)	0.02	Orthogroups_2024-Update
HORVU1Hr1G058880.2	No alias	multifunctional enzyme *(MFP)	0.02	Orthogroups_2024-Update
HORVU6Hr1G024100.1	No alias	multifunctional enzyme *(MFP)	0.03	Orthogroups_2024-Update
Sopen01g028270	No alias	Enoyl-CoA hydratase/isomerase family	0.04	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	InterProScan predictions
MF	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	IEA	InterProScan predictions
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006631	fatty acid metabolic process	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	InterProScan predictions
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0032787	monocarboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
BP	GO:0071704	organic substance metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003883	CTP synthase activity	IEP	Predicted GO
MF	GO:0004826	phenylalanine-tRNA ligase activity	IEP	Predicted GO
BP	GO:0006099	tricarboxylic acid cycle	IEP	Predicted GO
BP	GO:0006101	citrate metabolic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006432	phenylalanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006553	lysine metabolic process	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0006897	endocytosis	IEP	Predicted GO
MF	GO:0008131	primary amine oxidase activity	IEP	Predicted GO
MF	GO:0008839	4-hydroxy-tetrahydrodipicolinate reductase	IEP	Predicted GO
BP	GO:0009085	lysine biosynthetic process	IEP	Predicted GO
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015893	drug transport	IEP	Predicted GO
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Predicted GO
MF	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	IEP	Predicted GO
BP	GO:0016999	antibiotic metabolic process	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
BP	GO:0042255	ribosome assembly	IEP	Predicted GO
BP	GO:0042256	mature ribosome assembly	IEP	Predicted GO
MF	GO:0043021	ribonucleoprotein complex binding	IEP	Predicted GO
MF	GO:0043022	ribosome binding	IEP	Predicted GO
MF	GO:0043531	ADP binding	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0046451	diaminopimelate metabolic process	IEP	Predicted GO
MF	GO:0048038	quinone binding	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
BP	GO:0070925	organelle assembly	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
BP	GO:0072350	tricarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0098657	import into cell	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001753	Enoyl-CoA_hydra/iso	115	209
IPR001753	Enoyl-CoA_hydra/iso	7	69
IPR006108	3HC_DH_C	435	528
IPR006176	3-OHacyl-CoA_DH_NAD-bd	254	432

External Links

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PSME_00020187-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation