PSME_00020548-RA

Description : (at5g57090 : 686.0) Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity.; ETHYLENE INSENSITIVE ROOT 1 (EIR1); CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT2G01420.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5smq9|pin1_orysa : 637.0) Auxin efflux carrier component 1 (OsPIN1) (Ethylene insensitive root 1 homolog) - Oryza sativa (Rice) & (reliability: 1372.0) & (original description: no original description)

Gene families : OG_42_0000235 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000235_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00020548-RA
Cluster	HCCA clusters: Cluster_116

Target	Alias	Description	ECC score	Gene Family Method
102666	No alias	Auxin efflux carrier family protein	0.02	Orthogroups_2024-Update
234325	No alias	Auxin efflux carrier family protein	0.02	Orthogroups_2024-Update
A4A49_06506	No alias	auxin efflux carrier component 3	0.02	Orthogroups_2024-Update
A4A49_08912	No alias	auxin efflux carrier component 5	0.03	Orthogroups_2024-Update
A4A49_35848	No alias	hypothetical protein	0.03	Orthogroups_2024-Update
At1g70940	No alias	Auxin efflux carrier component 3...	0.03	Orthogroups_2024-Update
At5g16530	No alias	Auxin efflux carrier component...	0.03	Orthogroups_2024-Update
At5g57090	No alias	Auxin efflux carrier component 2...	0.02	Orthogroups_2024-Update
Bradi3g59520	No alias	Auxin efflux carrier family protein	0.03	Orthogroups_2024-Update
Brara.B01244.1	No alias	auxin transporter (PIN) & auxin efflux transporter (PIN)	0.04	Orthogroups_2024-Update
Brara.B02062.1	No alias	auxin transporter (PIN) & auxin efflux transporter (PIN)	0.02	Orthogroups_2024-Update
Glyma.17G057300	No alias	Auxin efflux carrier family protein	0.02	Orthogroups_2024-Update
Glyma.20G014300	No alias	Auxin efflux carrier family protein	0.03	Orthogroups_2024-Update
Mp6g07950.1	No alias	auxin transporter (PIN). auxin efflux transporter (PIN)	0.02	Orthogroups_2024-Update
PSME_00016874-RA	No alias	(at1g70940 : 775.0) A regulator of auxin efflux and...	0.04	Orthogroups_2024-Update
PSME_00036388-RA	No alias	(at1g70940 : 405.0) A regulator of auxin efflux and...	0.05	Orthogroups_2024-Update
PSME_00040058-RA	No alias	(at5g57090 : 363.0) Encodes an auxin efflux carrier that...	0.04	Orthogroups_2024-Update
PSME_00049001-RA	No alias	(at5g57090 : 117.0) Encodes an auxin efflux carrier that...	0.05	Orthogroups_2024-Update
Potri.002G072200	No alias	Auxin efflux carrier family protein	0.04	Orthogroups_2024-Update
Seita.4G101300.1	No alias	auxin efflux transporter (PIN) & auxin transporter (PIN)	0.02	Orthogroups_2024-Update
Seita.5G241500.1	No alias	auxin efflux transporter (PIN) & auxin transporter (PIN)	0.04	Orthogroups_2024-Update
Solyc04g007690	No alias	SlPIN3	0.02	Orthogroups_2024-Update
Solyc07g006900	No alias	SlPIN2	0.02	Orthogroups_2024-Update
Sopen05g003900	No alias	Membrane transport protein	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0008150	biological_process	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions

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Type	GO Term	Name	Evidence	Source
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004806	triglyceride lipase activity	IEP	Predicted GO
MF	GO:0005506	iron ion binding	IEP	Predicted GO
CC	GO:0005576	extracellular region	IEP	Predicted GO
CC	GO:0005618	cell wall	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
BP	GO:0007062	sister chromatid cohesion	IEP	Predicted GO
BP	GO:0007064	mitotic sister chromatid cohesion	IEP	Predicted GO
BP	GO:0009116	nucleoside metabolic process	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016762	xyloglucan:xyloglucosyl transferase activity	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016830	carbon-carbon lyase activity	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
CC	GO:0030312	external encapsulating structure	IEP	Predicted GO
CC	GO:0031390	Ctf18 RFC-like complex	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
CC	GO:0048046	apoplast	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:1901657	glycosyl compound metabolic process	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004776	Mem_trans	10	691

External Links

No external refs found!

PSME_00020548-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation