Description : (at4g21980 : 140.0) Encodes APG8, a component of autophagy conjugation pathway. Delivered to the lumens of vacuole under nitrogen-starvation condition. Highest expression in flowers. mRNA abundance increased during dark-induced carbon starvation. Predominantly cytoplasmic with or without N starvation. Upon concanamycin A the protein accumulates in the central vacuole as punctuate structures that resemble autophagic bodies. This localization is more abundant upon N starvation.; AUTOPHAGY 8A (APG8A); FUNCTIONS IN: APG8-specific protease activity, APG8 activating enzyme activity, Atg8 ligase activity; INVOLVED IN: autophagy; LOCATED IN: vacuolar lumen, autophagic vacuole, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241); BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT4G04620.2); Has 1531 Blast hits to 1529 proteins in 269 species: Archae - 0; Bacteria - 0; Metazoa - 726; Fungi - 172; Plants - 305; Viruses - 3; Other Eukaryotes - 325 (source: NCBI BLink). & (reliability: 280.0) & (original description: no original description)
Gene families : OG_42_0000932 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000932_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00020729-RA | |
Cluster | HCCA clusters: Cluster_114 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_35038 | No alias | autophagy-related protein 8f | 0.03 | Orthogroups_2024-Update | |
Bradi1g26400 | No alias | Ubiquitin-like superfamily protein | 0.02 | Orthogroups_2024-Update | |
Mp5g05930.1 | No alias | ATG8 autophagosome ubiquitin-fold protein | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000045 | autophagosome assembly | IEP | Predicted GO |
MF | GO:0004150 | dihydroneopterin aldolase activity | IEP | Predicted GO |
CC | GO:0005741 | mitochondrial outer membrane | IEP | Predicted GO |
CC | GO:0005750 | mitochondrial respiratory chain complex III | IEP | Predicted GO |
BP | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c | IEP | Predicted GO |
BP | GO:0006760 | folic acid-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0007033 | vacuole organization | IEP | Predicted GO |
BP | GO:0008104 | protein localization | IEP | Predicted GO |
BP | GO:0015031 | protein transport | IEP | Predicted GO |
BP | GO:0015833 | peptide transport | IEP | Predicted GO |
BP | GO:0016192 | vesicle-mediated transport | IEP | Predicted GO |
BP | GO:0016197 | endosomal transport | IEP | Predicted GO |
BP | GO:0016482 | cytosolic transport | IEP | Predicted GO |
MF | GO:0016832 | aldehyde-lyase activity | IEP | Predicted GO |
CC | GO:0019867 | outer membrane | IEP | Predicted GO |
BP | GO:0022904 | respiratory electron transport chain | IEP | Predicted GO |
CC | GO:0030906 | retromer, cargo-selective complex | IEP | Predicted GO |
CC | GO:0031966 | mitochondrial membrane | IEP | Predicted GO |
CC | GO:0031968 | organelle outer membrane | IEP | Predicted GO |
CC | GO:0032991 | protein-containing complex | IEP | Predicted GO |
BP | GO:0033036 | macromolecule localization | IEP | Predicted GO |
BP | GO:0042147 | retrograde transport, endosome to Golgi | IEP | Predicted GO |
BP | GO:0042558 | pteridine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0042886 | amide transport | IEP | Predicted GO |
BP | GO:0043603 | cellular amide metabolic process | IEP | Predicted GO |
CC | GO:0044429 | mitochondrial part | IEP | Predicted GO |
CC | GO:0044444 | cytoplasmic part | IEP | Predicted GO |
CC | GO:0044455 | mitochondrial membrane part | IEP | Predicted GO |
CC | GO:0044464 | cell part | IEP | Predicted GO |
BP | GO:0045184 | establishment of protein localization | IEP | Predicted GO |
CC | GO:0045275 | respiratory chain complex III | IEP | Predicted GO |
BP | GO:0046907 | intracellular transport | IEP | Predicted GO |
BP | GO:0051641 | cellular localization | IEP | Predicted GO |
BP | GO:0051649 | establishment of localization in cell | IEP | Predicted GO |
CC | GO:0070069 | cytochrome complex | IEP | Predicted GO |
BP | GO:0070925 | organelle assembly | IEP | Predicted GO |
BP | GO:0071702 | organic substance transport | IEP | Predicted GO |
BP | GO:0071705 | nitrogen compound transport | IEP | Predicted GO |
CC | GO:0098588 | bounding membrane of organelle | IEP | Predicted GO |
CC | GO:0098796 | membrane protein complex | IEP | Predicted GO |
CC | GO:0098798 | mitochondrial protein complex | IEP | Predicted GO |
CC | GO:0098800 | inner mitochondrial membrane protein complex | IEP | Predicted GO |
CC | GO:0098803 | respiratory chain complex | IEP | Predicted GO |
CC | GO:0098805 | whole membrane | IEP | Predicted GO |
BP | GO:1905037 | autophagosome organization | IEP | Predicted GO |
CC | GO:1990204 | oxidoreductase complex | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR004241 | Atg8-like | 3 | 88 |
No external refs found! |