PSME_00021355-RA


Description : "(at2g47460 : 196.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p10290|mybc_maize : 190.0) Anthocyanin regulatory C1 protein - Zea mays (Maize) & (reliability: 392.0) & (original description: no original description)"


Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00021355-RA
Cluster HCCA clusters: Cluster_410

Target Alias Description ECC score Gene Family Method Actions
A4A49_34066 No alias transcription factor rax3 0.05 Orthogroups_2024-Update
Bradi3g18977 No alias myb domain protein 36 0.03 Orthogroups_2024-Update
Bradi4g26180 No alias myb domain protein 60 0.04 Orthogroups_2024-Update
Brara.G00616.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
GRMZM2G395672 No alias myb domain protein 5 0.03 Orthogroups_2024-Update
Glyma.05G211200 No alias myb domain protein 103 0.04 Orthogroups_2024-Update
Glyma.19G024700 No alias myb domain protein 16 0.03 Orthogroups_2024-Update
Glyma.19G164600 No alias myb domain protein 15 0.03 Orthogroups_2024-Update
LOC_Os12g33070 No alias myb-like DNA-binding domain containing protein,... 0.03 Orthogroups_2024-Update
MA_10859g0010 No alias (at5g57620 : 230.0) Encodes a putative transcription... 0.02 Orthogroups_2024-Update
MA_308669g0010 No alias (p20025|myb38_maize : 236.0) Myb-related protein Zm38 -... 0.02 Orthogroups_2024-Update
PSME_00018444-RA No alias (at1g22640 : 194.0) MYB-type transcription factor (MYB3)... 0.05 Orthogroups_2024-Update
PSME_00023605-RA No alias (p20026|myb1_horvu : 272.0) Myb-related protein Hv1 -... 0.05 Orthogroups_2024-Update
PSME_00035306-RA No alias (at5g57620 : 246.0) Encodes a putative transcription... 0.03 Orthogroups_2024-Update
Potri.004G174400 No alias myb domain protein 4 0.03 Orthogroups_2024-Update
Potri.005G164900 No alias myb domain protein 93 0.02 Orthogroups_2024-Update
Potri.005G224100 No alias myb domain protein 15 0.05 Orthogroups_2024-Update
Pp1s211_139V6 No alias myb55 (myb domain protein 55) dna binding transcription factor 0.03 Orthogroups_2024-Update
Seita.2G213200.1 No alias MYB class-R2R3 subgroup-14 transcription factor 0.04 Orthogroups_2024-Update
Solyc08g082890 No alias R2R3MYB transcription factor 9 0.04 Orthogroups_2024-Update
Sopen12g033830 No alias Myb-like DNA-binding domain 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0008289 lipid binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 67 111
IPR001005 SANT/Myb 14 61
No external refs found!