Description : "(at2g47460 : 196.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p10290|mybc_maize : 190.0) Anthocyanin regulatory C1 protein - Zea mays (Maize) & (reliability: 392.0) & (original description: no original description)"
Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00021355-RA | |
Cluster | HCCA clusters: Cluster_410 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_34066 | No alias | transcription factor rax3 | 0.05 | Orthogroups_2024-Update | |
Bradi3g18977 | No alias | myb domain protein 36 | 0.03 | Orthogroups_2024-Update | |
Bradi4g26180 | No alias | myb domain protein 60 | 0.04 | Orthogroups_2024-Update | |
Brara.G00616.1 | No alias | MYB class-R2R3 transcription factor | 0.04 | Orthogroups_2024-Update | |
GRMZM2G395672 | No alias | myb domain protein 5 | 0.03 | Orthogroups_2024-Update | |
Glyma.05G211200 | No alias | myb domain protein 103 | 0.04 | Orthogroups_2024-Update | |
Glyma.19G024700 | No alias | myb domain protein 16 | 0.03 | Orthogroups_2024-Update | |
Glyma.19G164600 | No alias | myb domain protein 15 | 0.03 | Orthogroups_2024-Update | |
LOC_Os12g33070 | No alias | myb-like DNA-binding domain containing protein,... | 0.03 | Orthogroups_2024-Update | |
MA_10859g0010 | No alias | (at5g57620 : 230.0) Encodes a putative transcription... | 0.02 | Orthogroups_2024-Update | |
MA_308669g0010 | No alias | (p20025|myb38_maize : 236.0) Myb-related protein Zm38 -... | 0.02 | Orthogroups_2024-Update | |
PSME_00018444-RA | No alias | (at1g22640 : 194.0) MYB-type transcription factor (MYB3)... | 0.05 | Orthogroups_2024-Update | |
PSME_00023605-RA | No alias | (p20026|myb1_horvu : 272.0) Myb-related protein Hv1 -... | 0.05 | Orthogroups_2024-Update | |
PSME_00035306-RA | No alias | (at5g57620 : 246.0) Encodes a putative transcription... | 0.03 | Orthogroups_2024-Update | |
Potri.004G174400 | No alias | myb domain protein 4 | 0.03 | Orthogroups_2024-Update | |
Potri.005G164900 | No alias | myb domain protein 93 | 0.02 | Orthogroups_2024-Update | |
Potri.005G224100 | No alias | myb domain protein 15 | 0.05 | Orthogroups_2024-Update | |
Pp1s211_139V6 | No alias | myb55 (myb domain protein 55) dna binding transcription factor | 0.03 | Orthogroups_2024-Update | |
Seita.2G213200.1 | No alias | MYB class-R2R3 subgroup-14 transcription factor | 0.04 | Orthogroups_2024-Update | |
Solyc08g082890 | No alias | R2R3MYB transcription factor 9 | 0.04 | Orthogroups_2024-Update | |
Sopen12g033830 | No alias | Myb-like DNA-binding domain | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008289 | lipid binding | IEP | Predicted GO |
No external refs found! |