PSME_00021631-RA


Description : (at3g23780 : 373.0) This gene encodes the second largest, catalytic subunit of the nuclear DNA-dependent RNA polymerase IV (aka RNA polymerase D). The NRPD2 protein is found at nuclear foci that overlap or are adjacent to chromocentromeres but are not fully coincident with chromocentromeres. The loss of NRPD2 leads to the loss of cytosine methylation at pericentromeric 5S genes and AtSN1 retroelements but has no discernible effect on centromere repeat methylation. This suggests that Pol IV primarily affects facultative heterochromatin rather than constitutive heterochromatin.; nuclear RNA polymerase D2A (NRPD2A); CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, subunit 2, domain 6 (InterPro:IPR007120), RNA polymerase Rpb2, domain 7 (InterPro:IPR007641), RNA polymerase, beta subunit, protrusion (InterPro:IPR007644), RNA polymerase Rpb2, domain 3 (InterPro:IPR007645), DNA-directed RNA polymerase, subunit 2 (InterPro:IPR015712), RNA polymerase Rpb2, domain 2 (InterPro:IPR007642), RNA polymerase Rpb2, domain 4 (InterPro:IPR007646), RNA polymerase, beta subunit, conserved site (InterPro:IPR007121), RNA polymerase Rpb2, domain 5 (InterPro:IPR007647); BEST Arabidopsis thaliana protein match is: nuclear RNA polymerase D2B (TAIR:AT3G18090.1). & (reliability: 746.0) & (original description: no original description)


Gene families : OG_42_0022584 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00021631-RA
Cluster HCCA clusters: Cluster_230


Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEA InterProScan predictions
BP GO:0006351 transcription, DNA-templated IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003909 DNA ligase activity IEP Predicted GO
MF GO:0003910 DNA ligase (ATP) activity IEP Predicted GO
BP GO:0005985 sucrose metabolic process IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006310 DNA recombination IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
MF GO:0016157 sucrose synthase activity IEP Predicted GO
MF GO:0016597 amino acid binding IEP Predicted GO
MF GO:0016743 carboxyl- or carbamoyltransferase activity IEP Predicted GO
MF GO:0016886 ligase activity, forming phosphoric ester bonds IEP Predicted GO
BP GO:0019321 pentose metabolic process IEP Predicted GO
BP GO:0019566 arabinose metabolic process IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
BP GO:0046373 L-arabinose metabolic process IEP Predicted GO
MF GO:0046556 alpha-L-arabinofuranosidase activity IEP Predicted GO
MF GO:0046872 metal ion binding IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
InterPro domains Description Start Stop
IPR007642 RNA_pol_Rpb2_2 204 342
IPR007644 RNA_pol_bsu_protrusion 16 380
No external refs found!