PSME_00021651-RA


Description : (at1g15750 : 397.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 794.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00021651-RA
Cluster HCCA clusters: Cluster_69

Target Alias Description ECC score Gene Family Method Actions
A4A49_28074 No alias topless-related protein 1 0.03 Orthogroups_2024-Update
Brara.F01080.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.03 Orthogroups_2024-Update
PSME_00010135-RA No alias (at1g15750 : 426.0) Encodes a protein with several WD40... 0.05 Orthogroups_2024-Update
PSME_00022718-RA No alias (at1g15750 : 622.0) Encodes a protein with several WD40... 0.03 Orthogroups_2024-Update
PSME_00023926-RA No alias (at1g80490 : 545.0) TOPLESS-related 1 (TPR1); INVOLVED... 0.03 Orthogroups_2024-Update
PSME_00026092-RA No alias (at1g15750 : 221.0) Encodes a protein with several WD40... 0.06 Orthogroups_2024-Update
PSME_00046579-RA No alias (at1g80490 : 179.0) TOPLESS-related 1 (TPR1); INVOLVED... 0.03 Orthogroups_2024-Update
PSME_00048402-RA No alias (at3g16830 : 103.0) TOPLESS-related 2 (TPR2); FUNCTIONS... 0.02 Orthogroups_2024-Update
Potri.003G030000 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Potri.018G023800 No alias TOPLESS-related 1 0.05 Orthogroups_2024-Update
Potri.018G023900 No alias TOPLESS-related 1 0.03 Orthogroups_2024-Update
Solyc08g029050 No alias TOPLESS 6 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 257 291
No external refs found!