Description : (p28002|comt1_medsa : 233.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Medicago sativa (Alfalfa) & (at5g54160 : 220.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 416.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00023722-RA | |
Cluster | HCCA clusters: Cluster_41 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_36761 | No alias | caffeic acid 3-o-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
Bradi4g18065 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
Brara.G03470.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
GRMZM2G085924 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
GRMZM2G140996 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.04G227700 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
Glyma.12G109800 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
Glyma.20G176100 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
HORVU1Hr1G076670.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
HORVU7Hr1G117890.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
MA_10432987g0020 | No alias | (p28002|comt1_medsa : 228.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00008876-RA | No alias | (p93324|chomt_medsa : 161.0) Isoliquiritigenin... | 0.02 | Orthogroups_2024-Update | |
PSME_00009784-RA | No alias | (p28002|comt1_medsa : 427.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00009826-RA | No alias | (p28002|comt1_medsa : 234.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00016835-RA | No alias | (p28002|comt1_medsa : 153.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00021109-RA | No alias | (q8w013|comt1_catro : 194.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00030764-RA | No alias | (q8w013|comt1_catro : 213.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00034122-RA | No alias | (at5g54160 : 196.0) A caffeic acid/5-hydroxyferulic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00037447-RA | No alias | (q8w013|comt1_catro : 270.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00041945-RA | No alias | (q8w013|comt1_catro : 154.0) Caffeic acid... | 0.05 | Orthogroups_2024-Update | |
PSME_00051481-RA | No alias | (q8w013|comt1_catro : 234.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00052449-RA | No alias | (q8w013|comt1_catro : 208.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00052715-RA | No alias | (p28002|comt1_medsa : 235.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
Sobic.007G074800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Solyc06g060200 | No alias | Caffeic acid O-methyltransferase (AHRD V3.3 *-* Q2HTB3_MEDTR) | 0.03 | Orthogroups_2024-Update | |
Sopen10g003990 | No alias | O-methyltransferase | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004652 | polynucleotide adenylyltransferase activity | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006367 | transcription initiation from RNA polymerase II promoter | IEP | Predicted GO |
BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
MF | GO:0008017 | microtubule binding | IEP | Predicted GO |
MF | GO:0008092 | cytoskeletal protein binding | IEP | Predicted GO |
MF | GO:0008173 | RNA methyltransferase activity | IEP | Predicted GO |
BP | GO:0009143 | nucleoside triphosphate catabolic process | IEP | Predicted GO |
MF | GO:0015631 | tubulin binding | IEP | Predicted GO |
BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
MF | GO:0016788 | hydrolase activity, acting on ester bonds | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
BP | GO:0034641 | cellular nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0034654 | nucleobase-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0043631 | RNA polyadenylation | IEP | Predicted GO |
BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
MF | GO:0047429 | nucleoside-triphosphate diphosphatase activity | IEP | Predicted GO |
MF | GO:0070566 | adenylyltransferase activity | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
BP | GO:1901360 | organic cyclic compound metabolic process | IEP | Predicted GO |
No external refs found! |