PSME_00023768-RA


Description : (at5g17920 : 1243.0) Encodes a cytosolic cobalamin-independent methionine synthase, involved in methionine regeneration via the activated methyl cycle (SAM cycle). The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide.; COBALAMIN-INDEPENDENT METHIONINE SYNTHASE (ATCIMS); FUNCTIONS IN: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity, methionine synthase activity; INVOLVED IN: response to zinc ion, response to salt stress, methionine biosynthetic process; LOCATED IN: in 6 components; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: seedling growth, seed development stages; CONTAINS InterPro DOMAIN/s: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal (InterPro:IPR013215), Methionine synthase, vitamin-B12 independent (InterPro:IPR002629), 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (InterPro:IPR006276); BEST Arabidopsis thaliana protein match is: methionine synthase 2 (TAIR:AT3G03780.3); Has 4442 Blast hits to 4434 proteins in 1682 species: Archae - 183; Bacteria - 3246; Metazoa - 14; Fungi - 206; Plants - 251; Viruses - 2; Other Eukaryotes - 540 (source: NCBI BLink). & (q42699|mete_catro : 1239.0) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Vitamin-B12-independent methionine synthase isozyme) (Cobalamin-independent methionine synthase isozyme) - Catharanthus roseus (Rosy periwinkle) (Madag & (reliability: 2486.0) & (original description: no original description)


Gene families : OG_42_0002037 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002037_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00023768-RA
Cluster HCCA clusters: Cluster_5

Target Alias Description ECC score Gene Family Method Actions
171028 No alias Cobalamin-independent synthase family protein 0.04 Orthogroups_2024-Update
A4A49_56331 No alias 5-methyltetrahydropteroyltriglutamate--homocysteine... 0.04 Orthogroups_2024-Update
A4A49_56364 No alias 5-methyltetrahydropteroyltriglutamate--homocysteine... 0.02 Orthogroups_2024-Update
Cre03.g180750 No alias methionine synthase 3 0.02 Orthogroups_2024-Update
Glyma.19G114500 No alias Cobalamin-independent synthase family protein 0.04 Orthogroups_2024-Update
LOC_Os12g42884 No alias 5-methyltetrahydropteroyltriglutamate--homocysteine... 0.03 Orthogroups_2024-Update
MA_10090g0010 No alias (q42699|mete_catro : 1086.0)... 0.03 Orthogroups_2024-Update
Potri.004G190900 No alias Cobalamin-independent synthase family protein 0.03 Orthogroups_2024-Update
Potri.019G038200 No alias Cobalamin-independent synthase family protein 0.03 Orthogroups_2024-Update
Pp1s27_81V6 No alias vitamin-b12 independent methionine... 0.02 Orthogroups_2024-Update
Solyc10g081510 No alias ethylene-responsive methionine synthase 0.02 Orthogroups_2024-Update
Sopen01g004650 No alias Cobalamin-independent synthase, Catalytic domain 0.02 Orthogroups_2024-Update
Sopen10g032020 No alias Cobalamin-independent synthase, Catalytic domain 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEA InterProScan predictions
MF GO:0008270 zinc ion binding IEA InterProScan predictions
BP GO:0008652 cellular amino acid biosynthetic process IEA InterProScan predictions
BP GO:0009086 methionine biosynthetic process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0004107 chorismate synthase activity IEP Predicted GO
MF GO:0004470 malic enzyme activity IEP Predicted GO
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Predicted GO
MF GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IEP Predicted GO
MF GO:0004512 inositol-3-phosphate synthase activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0004674 protein serine/threonine kinase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005856 cytoskeleton IEP Predicted GO
CC GO:0005885 Arp2/3 protein complex IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006007 glucose catabolic process IEP Predicted GO
BP GO:0006020 inositol metabolic process IEP Predicted GO
BP GO:0006021 inositol biosynthetic process IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006487 protein N-linked glycosylation IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006891 intra-Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0007015 actin filament organization IEP Predicted GO
BP GO:0008064 regulation of actin polymerization or depolymerization IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008198 ferrous iron binding IEP Predicted GO
CC GO:0008250 oligosaccharyltransferase complex IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009072 aromatic amino acid family metabolic process IEP Predicted GO
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0010215 cellulose microfibril organization IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
BP GO:0010638 positive regulation of organelle organization IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015098 molybdate ion transmembrane transporter activity IEP Predicted GO
CC GO:0015629 actin cytoskeleton IEP Predicted GO
BP GO:0015689 molybdate ion transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016049 cell growth IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016615 malate dehydrogenase activity IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
MF GO:0016868 intramolecular transferase activity, phosphotransferases IEP Predicted GO
MF GO:0016872 intramolecular lyase activity IEP Predicted GO
CC GO:0017119 Golgi transport complex IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019320 hexose catabolic process IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
CC GO:0030176 integral component of endoplasmic reticulum membrane IEP Predicted GO
BP GO:0030198 extracellular matrix organization IEP Predicted GO
BP GO:0030832 regulation of actin filament length IEP Predicted GO
BP GO:0030833 regulation of actin filament polymerization IEP Predicted GO
BP GO:0030838 positive regulation of actin filament polymerization IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
CC GO:0031225 anchored component of membrane IEP Predicted GO
CC GO:0031227 intrinsic component of endoplasmic reticulum membrane IEP Predicted GO
BP GO:0031334 positive regulation of protein complex assembly IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
BP GO:0032271 regulation of protein polymerization IEP Predicted GO
BP GO:0032273 positive regulation of protein polymerization IEP Predicted GO
BP GO:0032535 regulation of cellular component size IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0032956 regulation of actin cytoskeleton organization IEP Predicted GO
BP GO:0032970 regulation of actin filament-based process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033043 regulation of organelle organization IEP Predicted GO
BP GO:0034314 Arp2/3 complex-mediated actin nucleation IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0040007 growth IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0043062 extracellular structure organization IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0043254 regulation of protein complex assembly IEP Predicted GO
BP GO:0044087 regulation of cellular component biogenesis IEP Predicted GO
BP GO:0044089 positive regulation of cellular component biogenesis IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044432 endoplasmic reticulum part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045010 actin nucleation IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046165 alcohol biosynthetic process IEP Predicted GO
BP GO:0046173 polyol biosynthetic process IEP Predicted GO
BP GO:0046365 monosaccharide catabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0051128 regulation of cellular component organization IEP Predicted GO
BP GO:0051130 positive regulation of cellular component organization IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0051493 regulation of cytoskeleton organization IEP Predicted GO
BP GO:0051495 positive regulation of cytoskeleton organization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090066 regulation of anatomical structure size IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
BP GO:0097435 supramolecular fiber organization IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
BP GO:0110053 regulation of actin filament organization IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
BP GO:1902903 regulation of supramolecular fiber organization IEP Predicted GO
BP GO:1902905 positive regulation of supramolecular fiber organization IEP Predicted GO
InterPro domains Description Start Stop
IPR013215 Cbl-indep_Met_Synth_N 8 322
IPR002629 Met_Synth_C/arc 438 761
No external refs found!