PSME_00023864-RA

Description : (at5g35520 : 125.0) encodes a homologue of the yeast (S. pombe) Mis12 (minichromosome instability) protein. MIS12 co-localizes with 180 bp repeats of centromeric DNA throughout the cell cycle with a similar pattern to AtCENH3/HTR12. Neither of these two proteins completely cover the 180 bp regions based on FISH analysis.; MINICHROMOSOME INSTABILITY 12 (MIS12)-LIKE (MIS12); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: mitosis, cell cycle; LOCATED IN: chromosome, centromeric region, nucleus; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Centromere protein Mis12 (InterPro:IPR008685); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 250.0) & (original description: no original description)

Gene families : OG_42_0007616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007616_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00023864-RA
Cluster	HCCA clusters: Cluster_7

Type	GO Term	Name	Evidence	Source
BP	GO:0000278	mitotic cell cycle	IEA	InterProScan predictions
CC	GO:0000775	chromosome, centromeric region	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	InterProScan predictions
BP	GO:0007049	cell cycle	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044427	chromosomal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
CC	GO:0098687	chromosomal region	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003729	mRNA binding	IEP	Predicted GO
MF	GO:0004807	triose-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005779	integral component of peroxisomal membrane	IEP	Predicted GO
CC	GO:0005849	mRNA cleavage factor complex	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
BP	GO:0006366	transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006378	mRNA polyadenylation	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0007034	vacuolar transport	IEP	Predicted GO
CC	GO:0009507	chloroplast	IEP	Predicted GO
CC	GO:0009521	photosystem	IEP	Predicted GO
CC	GO:0009522	photosystem I	IEP	Predicted GO
CC	GO:0009523	photosystem II	IEP	Predicted GO
CC	GO:0009536	plastid	IEP	Predicted GO
BP	GO:0010207	photosystem II assembly	IEP	Predicted GO
BP	GO:0015979	photosynthesis	IEP	Predicted GO
BP	GO:0016559	peroxisome fission	IEP	Predicted GO
MF	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
BP	GO:0031123	RNA 3'-end processing	IEP	Predicted GO
BP	GO:0031124	mRNA 3'-end processing	IEP	Predicted GO
CC	GO:0031231	intrinsic component of peroxisomal membrane	IEP	Predicted GO
CC	GO:0031300	intrinsic component of organelle membrane	IEP	Predicted GO
CC	GO:0031301	integral component of organelle membrane	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0043631	RNA polyadenylation	IEP	Predicted GO
CC	GO:0044436	thylakoid part	IEP	Predicted GO
CC	GO:0044438	microbody part	IEP	Predicted GO
CC	GO:0044439	peroxisomal part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
MF	GO:0045300	acyl-[acyl-carrier-protein] desaturase activity	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0048285	organelle fission	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR008685	Centromere_Mis12	44	173

External Links

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PSME_00023864-RA

Expression Profile

Co-expression Networks

Functional Annotation