PSME_00023991-RA

Description : (at2g34660 : 1469.0) encodes a multidrug resistance-associated protein that is MgATP-energized glutathione S-conjugate pump. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; multidrug resistance-associated protein 2 (MRP2); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2). & (q6yuu5|mdr_orysa : 199.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 2938.0) & (original description: no original description)

Gene families : OG_42_0125316 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00023991-RA
Cluster	HCCA clusters: Cluster_249

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003682	chromatin binding	IEP	Predicted GO
MF	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity	IEP	Predicted GO
MF	GO:0004177	aminopeptidase activity	IEP	Predicted GO
MF	GO:0004455	ketol-acid reductoisomerase activity	IEP	Predicted GO
MF	GO:0004525	ribonuclease III activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006338	chromatin remodeling	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Predicted GO
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0017056	structural constituent of nuclear pore	IEP	Predicted GO
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
CC	GO:0030906	retromer, cargo-selective complex	IEP	Predicted GO
MF	GO:0031491	nucleosome binding	IEP	Predicted GO
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043044	ATP-dependent chromatin remodeling	IEP	Predicted GO
MF	GO:0044877	protein-containing complex binding	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011527	ABC1_TM_dom	428	672
IPR003439	ABC_transporter-like	764	912
IPR003439	ABC_transporter-like	140	275

External Links

No external refs found!

PSME_00023991-RA

Expression Profile

Co-expression Networks

Functional Annotation