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  5. PSME_00025394-RA

PSME_00025394-RA


Description : (at3g22590 : 375.0) Encodes PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP), a homolog of human Paf1 Complex (Paf1C) subunit Parafibromin. Human Parafibromin assists in mediating output from the Wnt signaling pathway, and dysfunction of the encoding gene HRPT2 conditions specific cancer-related disease phenotypes. PHP resides in a ~670-kDa protein complex in nuclear extracts, and physically interacts with other known Paf1C-related proteins in vivo. Loss of PHP specifically conditioned accelerated phase transition from vegetative growth to flowering and resulted in misregulation of a very limited subset of genes that included the flowering repressor FLOWERING LOCUS C (FLC).; PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP); CONTAINS InterPro DOMAIN/s: RNA polymerase II accessory factor, Cdc73 (InterPro:IPR007852); Has 502 Blast hits to 395 proteins in 198 species: Archae - 0; Bacteria - 0; Metazoa - 257; Fungi - 127; Plants - 42; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink). & (reliability: 750.0) & (original description: no original description)


Gene families : OG_42_0003860 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003860_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00025394-RA
Cluster HCCA clusters: Cluster_109

Target Alias Description ECC score Gene Family Method Actions
LOC_Os03g46190 No alias parafibromin, putative, expressed 0.02 Orthogroups_2024-Update
MA_352945g0010 No alias (at3g22590 : 408.0) Encodes PLANT HOMOLOGOUS TO... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
BP GO:0000271 polysaccharide biosynthetic process IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0008033 tRNA processing IEP Predicted GO
MF GO:0008097 5S rRNA binding IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009250 glucan biosynthetic process IEP Predicted GO
BP GO:0016051 carbohydrate biosynthetic process IEP Predicted GO
MF GO:0016759 cellulose synthase activity IEP Predicted GO
MF GO:0016760 cellulose synthase (UDP-forming) activity IEP Predicted GO
MF GO:0019843 rRNA binding IEP Predicted GO
BP GO:0030243 cellulose metabolic process IEP Predicted GO
BP GO:0030244 cellulose biosynthetic process IEP Predicted GO
BP GO:0033692 cellular polysaccharide biosynthetic process IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0034637 cellular carbohydrate biosynthetic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
MF GO:0035251 UDP-glucosyltransferase activity IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0051273 beta-glucan metabolic process IEP Predicted GO
BP GO:0051274 beta-glucan biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR031336 CDC73_C 719 872
IPR031336 CDC73_C 241 370
IPR032041 Cdc73_N 415 544
IPR032041 Cdc73_N 6 135
No external refs found!