PSME_00025502-RA


Description : (at5g63910 : 237.0) Encodes a farnesylcysteine lyase (EC 1.8.3.5) involved in a salvage /detoxification pathway of farnesylcysteine (FC) residues that are liberated during the degradation of prenylated proteins. Because FC is a competitive inhibitor of prenylcysteine methyltransferases involved in the down-regulation of ABA signaling, fcly mutants with elevated FC levels are hypersensitive to ABA. The protein also appears to be glycosylated when translated in vitro in the presence of microsomal membranes and it likely requires FAD for enzymatic activity.; farnesylcysteine lyase (FCLY); FUNCTIONS IN: prenylcysteine oxidase activity; INVOLVED IN: prenylated protein catabolic process, abscisic acid mediated signaling pathway, farnesyl diphosphate metabolic process; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prenylcysteine lyase (InterPro:IPR010795), Prenylcysteine oxidase (InterPro:IPR017046); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 474.0) & (original description: no original description)


Gene families : OG_42_0004385 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004385_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00025502-RA
Cluster HCCA clusters: Cluster_131

Target Alias Description ECC score Gene Family Method Actions
PSME_00025390-RA No alias (at5g63910 : 209.0) Encodes a farnesylcysteine lyase (EC... 0.03 Orthogroups_2024-Update
PSME_00038125-RA No alias (at5g63910 : 273.0) Encodes a farnesylcysteine lyase (EC... 0.1 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor IEA InterProScan predictions
BP GO:0030328 prenylcysteine catabolic process IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR010795 Prenylcys_lyase 86 211
No external refs found!