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  5. PSME_00026136-RA

PSME_00026136-RA


Description : "(at2g47460 : 219.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p27898|mybp_maize : 213.0) Myb-related protein P - Zea mays (Maize) & (reliability: 438.0) & (original description: no original description)"


Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00026136-RA
Cluster HCCA clusters: Cluster_43

Target Alias Description ECC score Gene Family Method Actions
A4A49_08715 No alias myb-related protein pp2 0.03 Orthogroups_2024-Update
A4A49_11057 No alias transcription factor myb86 0.03 Orthogroups_2024-Update
At4g17785 No alias Transcription factor MYB39... 0.02 Orthogroups_2024-Update
At5g40330 No alias Transcription factor MYB23... 0.03 Orthogroups_2024-Update
Bradi2g11676 No alias myb domain protein 12 0.02 Orthogroups_2024-Update
Bradi5g15760 No alias myb domain protein 15 0.03 Orthogroups_2024-Update
Brara.F01643.1 No alias MYB class-R2R3 subgroup-16 transcription factor &... 0.03 Orthogroups_2024-Update
Brara.G01033.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.03 Orthogroups_2024-Update
GRMZM2G158700 No alias myb domain protein 112 0.02 Orthogroups_2024-Update
Glyma.05G040700 No alias myb domain protein 86 0.03 Orthogroups_2024-Update
Glyma.11G194100 No alias myb domain protein 36 0.02 Orthogroups_2024-Update
Glyma.17G031600 No alias myb domain protein 111 0.03 Orthogroups_2024-Update
HORVU5Hr1G021750.2 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
HORVU6Hr1G067380.1 No alias MYB class-R2R3 subgroup-3 transcription factor 0.03 Orthogroups_2024-Update
LOC_Os04g50770 No alias MYB family transcription factor, putative, expressed 0.03 Orthogroups_2024-Update
MA_1589g0010 No alias (at1g63910 : 241.0) member of MYB3R- and R2R3- type MYB-... 0.03 Orthogroups_2024-Update
PSME_00014669-RA No alias (at1g22640 : 190.0) MYB-type transcription factor (MYB3)... 0.04 Orthogroups_2024-Update
PSME_00021697-RA No alias (at5g15310 : 302.0) Member of the R2R3 factor gene... 0.04 Orthogroups_2024-Update
PSME_00042064-RA No alias (p20026|myb1_horvu : 274.0) Myb-related protein Hv1 -... 0.02 Orthogroups_2024-Update
Potri.008G122100 No alias myb domain protein 62 0.02 Orthogroups_2024-Update
Potri.010G149900 No alias myb domain protein 108 0.02 Orthogroups_2024-Update
Seita.3G062400.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
Seita.5G274200.1 No alias MYB class-R2R3 subgroup-14 transcription factor 0.03 Orthogroups_2024-Update
Solyc05g053330 No alias MYB transcription factor (AHRD V3.3 *** Q39550_CRAPL) 0.03 Orthogroups_2024-Update
Sopen05g004950 No alias Myb-like DNA-binding domain 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0004418 hydroxymethylbilane synthase activity IEP Predicted GO
MF GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
BP GO:0006405 RNA export from nucleus IEP Predicted GO
BP GO:0006406 mRNA export from nucleus IEP Predicted GO
BP GO:0007165 signal transduction IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016790 thiolester hydrolase activity IEP Predicted GO
BP GO:0016973 poly(A)+ mRNA export from nucleus IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0033013 tetrapyrrole metabolic process IEP Predicted GO
BP GO:0033014 tetrapyrrole biosynthetic process IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
BP GO:0050657 nucleic acid transport IEP Predicted GO
BP GO:0050658 RNA transport IEP Predicted GO
BP GO:0051028 mRNA transport IEP Predicted GO
BP GO:0051168 nuclear export IEP Predicted GO
BP GO:0051236 establishment of RNA localization IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 72 112
IPR001005 SANT/Myb 14 61
No external refs found!