Description : (at4g21070 : 504.0) Encodes AtBRCA1, an ortholog of the human breast cancer susceptibility gene 1. Contains one N-terminal RING finger, two C-terminal BRCT and the p300/CBP interacting domain. Strongly induced by gamma rays, consistent with a putative role in DNA repair and in cell cycle control.; breast cancer susceptibility1 (BRCA1); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: DNA repair, response to gamma radiation; LOCATED IN: intracellular, nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), BRCA1 (InterPro:IPR011364), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer associated RING 1 (TAIR:AT1G04020.2); Has 8999 Blast hits to 8407 proteins in 1134 species: Archae - 0; Bacteria - 191; Metazoa - 6557; Fungi - 520; Plants - 721; Viruses - 32; Other Eukaryotes - 978 (source: NCBI BLink). & (reliability: 1008.0) & (original description: no original description)
Gene families : OG_42_0000927 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000927_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00026457-RA | |
Cluster | HCCA clusters: Cluster_63 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004523 | RNA-DNA hybrid ribonuclease activity | IEP | Predicted GO |
MF | GO:0004857 | enzyme inhibitor activity | IEP | Predicted GO |
MF | GO:0016788 | hydrolase activity, acting on ester bonds | IEP | Predicted GO |
MF | GO:0016840 | carbon-nitrogen lyase activity | IEP | Predicted GO |
MF | GO:0016843 | amine-lyase activity | IEP | Predicted GO |
MF | GO:0016844 | strictosidine synthase activity | IEP | Predicted GO |
MF | GO:0030234 | enzyme regulator activity | IEP | Predicted GO |
MF | GO:0030599 | pectinesterase activity | IEP | Predicted GO |
BP | GO:0042545 | cell wall modification | IEP | Predicted GO |
BP | GO:0045229 | external encapsulating structure organization | IEP | Predicted GO |
MF | GO:0052689 | carboxylic ester hydrolase activity | IEP | Predicted GO |
BP | GO:0071554 | cell wall organization or biogenesis | IEP | Predicted GO |
BP | GO:0071555 | cell wall organization | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001357 | BRCT_dom | 876 | 943 |
No external refs found! |