PSME_00027780-RA


Description : (p35063|h2ax_picab : 157.0) Histone H2AX - Picea abies (Norway spruce) (Picea excelsa) & (at1g54690 : 148.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 296.0) & (original description: no original description)


Gene families : OG_42_0000186 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000186_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00027780-RA
Cluster HCCA clusters: Cluster_195

Target Alias Description ECC score Gene Family Method Actions
At2g32750 No alias Exostosin family protein [Source:TAIR;Acc:AT2G32750] 0.06 Orthogroups_2024-Update
Glyma.20G004900 No alias Exostosin family protein 0.06 Orthogroups_2024-Update
Kfl00046_0180 kfl00046_0180_v1.... (at2g29040 : 174.0) Exostosin family protein; FUNCTIONS... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 237 257
IPR007125 Histone_H2A/H2B/H3 147 233
No external refs found!