PSME_00028557-RA


Description : (at5g58230 : 191.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 382.0) & (original description: no original description)


Gene families : OG_42_0126068 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00028557-RA
Cluster HCCA clusters: Cluster_94


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000776 kinetochore IEP Predicted GO
BP GO:0005984 disaccharide metabolic process IEP Predicted GO
BP GO:0005985 sucrose metabolic process IEP Predicted GO
MF GO:0008194 UDP-glycosyltransferase activity IEP Predicted GO
BP GO:0009311 oligosaccharide metabolic process IEP Predicted GO
MF GO:0016157 sucrose synthase activity IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016830 carbon-carbon lyase activity IEP Predicted GO
MF GO:0016831 carboxy-lyase activity IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
MF GO:0030170 pyridoxal phosphate binding IEP Predicted GO
CC GO:0031262 Ndc80 complex IEP Predicted GO
MF GO:0035251 UDP-glucosyltransferase activity IEP Predicted GO
MF GO:0070279 vitamin B6 binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 110 142
IPR001680 WD40_repeat 39 73
IPR001680 WD40_repeat 2 32
No external refs found!