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  5. PSME_00029397-RA

PSME_00029397-RA


Description : (p31251|ube12_wheat : 449.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at2g30110 : 435.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (reliability: 870.0) & (original description: no original description)


Gene families : OG_42_0126216 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00029397-RA
Cluster HCCA clusters: Cluster_742


Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005088 Ras guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005089 Rho guanyl-nucleotide exchange factor activity IEP Predicted GO
BP GO:0008272 sulfate transport IEP Predicted GO
MF GO:0010181 FMN binding IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015116 sulfate transmembrane transporter activity IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
MF GO:0017048 Rho GTPase binding IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
MF GO:0046983 protein dimerization activity IEP Predicted GO
BP GO:0072348 sulfur compound transport IEP Predicted GO
MF GO:1901682 sulfur compound transmembrane transporter activity IEP Predicted GO
InterPro domains Description Start Stop
IPR019572 UBA_E1_Cys 209 449
IPR000594 ThiF_NAD_FAD-bd 89 208
No external refs found!