PSME_00029691-RA


Description : (at2g30110 : 1397.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (p31251|ube12_wheat : 1387.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (reliability: 2794.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00029691-RA
Cluster HCCA clusters: Cluster_70


Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004185 serine-type carboxypeptidase activity IEP Predicted GO
MF GO:0004559 alpha-mannosidase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004869 cysteine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0005991 trehalose metabolic process IEP Predicted GO
BP GO:0005992 trehalose biosynthetic process IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006013 mannose metabolic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006778 porphyrin-containing compound metabolic process IEP Predicted GO
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Predicted GO
BP GO:0006783 heme biosynthetic process IEP Predicted GO
BP GO:0006784 heme a biosynthetic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006873 cellular ion homeostasis IEP Predicted GO
BP GO:0006875 cellular metal ion homeostasis IEP Predicted GO
BP GO:0006879 cellular iron ion homeostasis IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
MF GO:0008199 ferric iron binding IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
BP GO:0009312 oligosaccharide biosynthetic process IEP Predicted GO
MF GO:0015923 mannosidase activity IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0030003 cellular cation homeostasis IEP Predicted GO
BP GO:0033014 tetrapyrrole biosynthetic process IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0042168 heme metabolic process IEP Predicted GO
BP GO:0042440 pigment metabolic process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0046148 pigment biosynthetic process IEP Predicted GO
BP GO:0046160 heme a metabolic process IEP Predicted GO
BP GO:0046351 disaccharide biosynthetic process IEP Predicted GO
BP GO:0046916 cellular transition metal ion homeostasis IEP Predicted GO
MF GO:0046983 protein dimerization activity IEP Predicted GO
BP GO:0048878 chemical homeostasis IEP Predicted GO
BP GO:0050801 ion homeostasis IEP Predicted GO
MF GO:0051537 2 iron, 2 sulfur cluster binding IEP Predicted GO
BP GO:0055065 metal ion homeostasis IEP Predicted GO
BP GO:0055072 iron ion homeostasis IEP Predicted GO
BP GO:0055076 transition metal ion homeostasis IEP Predicted GO
BP GO:0055080 cation homeostasis IEP Predicted GO
BP GO:0055082 cellular chemical homeostasis IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0098771 inorganic ion homeostasis IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000594 ThiF_NAD_FAD-bd 84 462
IPR000594 ThiF_NAD_FAD-bd 480 972
IPR019572 UBA_E1_Cys 667 914
IPR032418 E1_FCCH 257 328
IPR018965 Ub-activating_enz_E1_C 984 1073
IPR032420 E1_4HB 329 398
No external refs found!