PSME_00030425-RA

Description : (q43116|pdi_ricco : 449.0) Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) - Ricinus communis (Castor bean) & (at1g77510 : 407.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; PDI-like 1-2 (PDIL1-2); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to cadmium ion, response to salt stress, response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane, chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Protein disulphide isomerase (InterPro:IPR005792), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 1-1 (TAIR:AT1G21750.1); Has 30299 Blast hits to 17128 proteins in 2902 species: Archae - 354; Bacteria - 14610; Metazoa - 5224; Fungi - 1567; Plants - 2445; Viruses - 29; Other Eukaryotes - 6070 (source: NCBI BLink). & (reliability: 814.0) & (original description: no original description)

Gene families : OG_42_0002283 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002283_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00030425-RA
Cluster	HCCA clusters: Cluster_179

Target	Alias	Description	ECC score	Gene Family Method
At1g77510	No alias	Protein disulfide isomerase-like 1-2...	0.02	Orthogroups_2024-Update
Bradi5g10610	No alias	PDI-like 1-2	0.03	Orthogroups_2024-Update
GRMZM2G091481	No alias	PDI-like 1-1	0.02	Orthogroups_2024-Update
Glyma.06G114800	No alias	PDI-like 1-2	0.02	Orthogroups_2024-Update
Seita.1G192800.1	No alias	protein disulfide isomerase *(PDI-L) & EC_5.3...	0.02	Orthogroups_2024-Update
Sopen06g001910	No alias	Thioredoxin	0.03	Orthogroups_2024-Update
Sopen06g020400	No alias	Thioredoxin	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005730	nucleolus	IEA	InterProScan predictions
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	InterProScan predictions
MF	GO:0008134	transcription factor binding	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045454	cell redox homeostasis	IEA	InterProScan predictions
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046914	transition metal ion binding	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007015	DNA_pol_V/MYBBP1A	374	461
IPR013766	Thioredoxin_domain	277	357
IPR013766	Thioredoxin_domain	3	100
IPR013766	Thioredoxin_domain	939	1029
IPR013766	Thioredoxin_domain	661	759

External Links

No external refs found!

PSME_00030425-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation