PSME_00031675-RA


Description : (at1g48050 : 94.7) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 189.4) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00031675-RA
Cluster HCCA clusters: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
PSME_00029027-RA No alias (at1g48050 : 171.0) Ku80 and ku70 form the heterodimer... 0.02 Orthogroups_2024-Update
PSME_00033536-RA No alias (at1g48050 : 111.0) Ku80 and ku70 form the heterodimer... 0.04 Orthogroups_2024-Update
PSME_00040052-RA No alias (at1g48050 : 96.7) Ku80 and ku70 form the heterodimer... 0.04 Orthogroups_2024-Update
PSME_00054000-RA No alias (at1g48050 : 87.8) Ku80 and ku70 form the heterodimer... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0000105 histidine biosynthetic process IEP Predicted GO
MF GO:0004399 histidinol dehydrogenase activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004867 serine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0005544 calcium-dependent phospholipid binding IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006547 histidine metabolic process IEP Predicted GO
MF GO:0008375 acetylglucosaminyltransferase activity IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009611 response to wounding IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
BP GO:0052803 imidazole-containing compound metabolic process IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!