Description : (at1g48050 : 94.7) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 189.4) & (original description: no original description)
Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00031675-RA | |
Cluster | HCCA clusters: Cluster_22 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
PSME_00029027-RA | No alias | (at1g48050 : 171.0) Ku80 and ku70 form the heterodimer... | 0.02 | Orthogroups_2024-Update | |
PSME_00033536-RA | No alias | (at1g48050 : 111.0) Ku80 and ku70 form the heterodimer... | 0.04 | Orthogroups_2024-Update | |
PSME_00040052-RA | No alias | (at1g48050 : 96.7) Ku80 and ku70 form the heterodimer... | 0.04 | Orthogroups_2024-Update | |
PSME_00054000-RA | No alias | (at1g48050 : 87.8) Ku80 and ku70 form the heterodimer... | 0.04 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000105 | histidine biosynthetic process | IEP | Predicted GO |
MF | GO:0004399 | histidinol dehydrogenase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
MF | GO:0004866 | endopeptidase inhibitor activity | IEP | Predicted GO |
MF | GO:0004867 | serine-type endopeptidase inhibitor activity | IEP | Predicted GO |
MF | GO:0005544 | calcium-dependent phospholipid binding | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0006547 | histidine metabolic process | IEP | Predicted GO |
MF | GO:0008375 | acetylglucosaminyltransferase activity | IEP | Predicted GO |
BP | GO:0009116 | nucleoside metabolic process | IEP | Predicted GO |
BP | GO:0009611 | response to wounding | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0030414 | peptidase inhibitor activity | IEP | Predicted GO |
BP | GO:0052803 | imidazole-containing compound metabolic process | IEP | Predicted GO |
MF | GO:0061134 | peptidase regulator activity | IEP | Predicted GO |
MF | GO:0061135 | endopeptidase regulator activity | IEP | Predicted GO |
BP | GO:1901657 | glycosyl compound metabolic process | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |