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  5. PSME_00032571-RA

PSME_00032571-RA


Description : (at3g24495 : 167.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (reliability: 334.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00032571-RA
Cluster HCCA clusters: Cluster_659

Target Alias Description ECC score Gene Family Method Actions
PSME_00003755-RA No alias (at3g24495 : 345.0) encodes a DNA mismatch repair... 0.05 Orthogroups_2024-Update
PSME_00015196-RA No alias (at3g24495 : 159.0) encodes a DNA mismatch repair... 0.04 Orthogroups_2024-Update
PSME_00048248-RA No alias (at3g24495 : 111.0) encodes a DNA mismatch repair... 0.05 Orthogroups_2024-Update
Seita.5G128200.1 No alias component *(MSH7) of MSH2-x mismatch repair heterodimers 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006298 mismatch repair IEA InterProScan predictions
MF GO:0030983 mismatched DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000432 DNA_mismatch_repair_MutS_C 116 177
No external refs found!