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  5. PSME_00033536-RA

PSME_00033536-RA


Description : (at1g48050 : 111.0) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 222.0) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00033536-RA
Cluster HCCA clusters: Cluster_279

Target Alias Description ECC score Gene Family Method Actions
PSME_00031675-RA No alias (at1g48050 : 94.7) Ku80 and ku70 form the heterodimer... 0.04 Orthogroups_2024-Update
PSME_00040052-RA No alias (at1g48050 : 96.7) Ku80 and ku70 form the heterodimer... 0.04 Orthogroups_2024-Update
PSME_00043235-RA No alias (at1g48050 : 112.0) Ku80 and ku70 form the heterodimer... 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004519 endonuclease activity IEP Predicted GO
MF GO:0004521 endoribonuclease activity IEP Predicted GO
MF GO:0004540 ribonuclease activity IEP Predicted GO
MF GO:0008131 primary amine oxidase activity IEP Predicted GO
MF GO:0008430 selenium binding IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0033897 ribonuclease T2 activity IEP Predicted GO
MF GO:0048038 quinone binding IEP Predicted GO
InterPro domains Description Start Stop
IPR014893 Ku_PK_bind 117 169
No external refs found!