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  5. PSME_00033660-RA

PSME_00033660-RA


Description : (p40280|h2a_maize : 149.0) Histone H2A - Zea mays (Maize) & (at1g08880 : 144.0) Encodes HTA5, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; H2AXA; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: gamma histone variant H2AX (TAIR:AT1G54690.1); Has 3916 Blast hits to 3911 proteins in 363 species: Archae - 0; Bacteria - 0; Metazoa - 2550; Fungi - 318; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 288.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00033660-RA
Cluster HCCA clusters: Cluster_163

Target Alias Description ECC score Gene Family Method Actions
GRMZM2G151726 No alias histone H2A 2 0.02 Orthogroups_2024-Update
HORVU5Hr1G069680.1 No alias histone *(H2A) 0.05 Orthogroups_2024-Update
HORVU7Hr1G100100.3 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU7Hr1G100110.4 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
HORVU7Hr1G100120.13 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
Mp2g00760.1 No alias histone (H2A) 0.02 Orthogroups_2024-Update
PSME_00050693-RA No alias (at4g27230 : 166.0) Encodes HTA2, a histone H2A... 0.09 Orthogroups_2024-Update
Sopen09g029130 No alias Core histone H2A/H2B/H3/H4 0.03 Orthogroups_2024-Update
evm.model.contig_533.4 No alias (p16866|h2a4_volca : 182.0) Histone H2A-IV - Volvox... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006334 nucleosome assembly IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006417 regulation of translation IEP Predicted GO
BP GO:0006448 regulation of translational elongation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
MF GO:0008509 anion transmembrane transporter activity IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010608 posttranscriptional regulation of gene expression IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
BP GO:0015698 inorganic anion transport IEP Predicted GO
BP GO:0015936 coenzyme A metabolic process IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0032268 regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034248 regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0034728 nucleosome organization IEP Predicted GO
MF GO:0043021 ribonucleoprotein complex binding IEP Predicted GO
MF GO:0043022 ribosome binding IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043244 regulation of protein complex disassembly IEP Predicted GO
BP GO:0043933 protein-containing complex subunit organization IEP Predicted GO
MF GO:0044877 protein-containing complex binding IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048522 positive regulation of cellular process IEP Predicted GO
BP GO:0051128 regulation of cellular component organization IEP Predicted GO
BP GO:0051130 positive regulation of cellular component organization IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051246 regulation of protein metabolic process IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0065003 protein-containing complex assembly IEP Predicted GO
BP GO:0065004 protein-DNA complex assembly IEP Predicted GO
BP GO:0071824 protein-DNA complex subunit organization IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR007125 Histone_H2A/H2B/H3 24 98
IPR007125 Histone_H2A/H2B/H3 153 239
IPR032454 Histone_H2A_C 101 134
IPR032454 Histone_H2A_C 242 275
No external refs found!