PSME_00034714-RA

Description : (p41380|if4a3_nicpl : 604.0) Eukaryotic initiation factor 4A-3 (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-3) (eIF-4A-3) - Nicotiana plumbaginifolia (Leadwort-leaved tobacco) & (at3g19760 : 578.0) Encodes an RNA helicase that may be a component of the Exon Junction Complex. Subcellular localization is modulated by stress. Under normal conditions it is localized to the nuceloplasm but under hyopoxic conditions it localizes to the nucleolus and splicing speckles.; eukaryotic initiation factor 4A-III (EIF4A-III); FUNCTIONS IN: protein binding, ATP-dependent helicase activity; INVOLVED IN: mRNA processing, response to hypoxia; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEA(D/H)-box RNA helicase family protein (TAIR:AT1G51380.1); Has 50040 Blast hits to 49280 proteins in 3163 species: Archae - 836; Bacteria - 27183; Metazoa - 6400; Fungi - 4843; Plants - 2693; Viruses - 42; Other Eukaryotes - 8043 (source: NCBI BLink). & (reliability: 1156.0) & (original description: no original description)

Gene families : OG_42_0000623 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000623_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00034714-RA
Cluster	HCCA clusters: Cluster_185

Target	Alias	Description	ECC score	Gene Family Method
164382	No alias	eukaryotic initiation factor 4A-III	0.02	Orthogroups_2024-Update
Brara.A03225.1	No alias	mRNA unwinding factor *(eIF4A))	0.02	Orthogroups_2024-Update
Brara.E02728.1	No alias	mRNA unwinding factor *(eIF4A))	0.03	Orthogroups_2024-Update
Brara.H00095.1	No alias	mRNA unwinding factor *(eIF4A))	0.03	Orthogroups_2024-Update
GRMZM2G018947	No alias	eukaryotic initiation factor 4A-III	0.02	Orthogroups_2024-Update
Glyma.15G171800	No alias	eukaryotic translation initiation factor 4A1	0.03	Orthogroups_2024-Update
Glyma.17G053200	No alias	eif4a-2	0.03	Orthogroups_2024-Update
HORVU7Hr1G073770.1	No alias	Unknown function	0.02	Orthogroups_2024-Update
LOC_Os03g36930	No alias	DEAD-box ATP-dependent RNA helicase, putative, expressed	0.03	Orthogroups_2024-Update
Pp1s136_29V6	No alias	MDC16.5; eukaryotic translation initiation factor 4A-1 /...	0.02	Orthogroups_2024-Update
Pp1s275_62V6	No alias	dead box atp-dependent rna	0.02	Orthogroups_2024-Update
Pp1s77_16V6	No alias	No description available	0.02	Orthogroups_2024-Update
Seita.1G089900.1	No alias	mRNA unwinding factor *(eIF4A))	0.04	Orthogroups_2024-Update
Seita.4G242200.1	No alias	mRNA unwinding factor *(eIF4A))	0.02	Orthogroups_2024-Update
Sobic.010G251100.1	No alias	mRNA unwinding factor *(eIF4A))	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
MF	GO:0008144	drug binding	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004576	oligosaccharyl transferase activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0005048	signal sequence binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006621	protein retention in ER lumen	IEP	Predicted GO
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Predicted GO
BP	GO:0007049	cell cycle	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016778	diphosphotransferase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
BP	GO:0032507	maintenance of protein location in cell	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Predicted GO
MF	GO:0042277	peptide binding	IEP	Predicted GO
MF	GO:0042393	histone binding	IEP	Predicted GO
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0045185	maintenance of protein location	IEP	Predicted GO
MF	GO:0046923	ER retention sequence binding	IEP	Predicted GO
MF	GO:0050290	sphingomyelin phosphodiesterase D activity	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051235	maintenance of location	IEP	Predicted GO
BP	GO:0051321	meiotic cell cycle	IEP	Predicted GO
BP	GO:0051651	maintenance of location in cell	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001650	Helicase_C	320	347
IPR001650	Helicase_C	244	308
IPR011545	DEAD/DEAH_box_helicase_dom	64	226

External Links

No external refs found!

PSME_00034714-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation