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Description : (p49730|rir2_tobac : 335.0) Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleoside-diphosphate reductase R2 subunit) - Nicotiana tabacum (Common tobacco) & (at3g27060 : 332.0) Encodes one of the 3 ribonucleotide reductase (RNR) small subunit genes. TSO2 transcription occurs predominantly at the S-phase of the cell cycle and its expression pattern is consistent with its role in dNDP biosynthesis during DNA replication in actively dividing cells. Critical for cell cycle progression, DNA damage repair and plant development.; TSO MEANING 'UGLY' IN CHINESE 2 (TSO2); FUNCTIONS IN: oxidoreductase activity, transition metal ion binding, ribonucleoside-diphosphate reductase activity; INVOLVED IN: in 6 processes; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase-related (InterPro:IPR012348), Ribonucleotide reductase (InterPro:IPR000358), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078); BEST Arabidopsis thaliana protein match is: ribonucleotide reductase 2A (TAIR:AT3G23580.1); Has 9355 Blast hits to 9350 proteins in 2299 species: Archae - 34; Bacteria - 4270; Metazoa - 263; Fungi - 240; Plants - 185; Viruses - 729; Other Eukaryotes - 3634 (source: NCBI BLink). & (reliability: 664.0) & (original description: no original description)
Gene families : OG_42_0127480 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Pseudotsuga release: PSME_00036532-RA | |
| Cluster | HCCA clusters: Cluster_77 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
| BP | GO:0006351 | transcription, DNA-templated | IEP | Predicted GO |
| MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
| BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
| MF | GO:0033926 | glycopeptide alpha-N-acetylgalactosaminidase activity | IEP | Predicted GO |
| MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
| BP | GO:0097659 | nucleic acid-templated transcription | IEP | Predicted GO |
| MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
| MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
| MF | GO:0140103 | catalytic activity, acting on a glycoprotein | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR000358 | RNR_small_fam | 7 | 251 |
| No external refs found! |