PSME_00037447-RA


Description : (q8w013|comt1_catro : 270.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 249.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3í-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3í-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 490.0) & (original description: no original description)


Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00037447-RA
Cluster HCCA clusters: Cluster_32

Target Alias Description ECC score Gene Family Method Actions
HORVU7Hr1G117890.1 No alias EC_2.1 transferase transferring one-carbon group 0.02 Orthogroups_2024-Update
LOC_Os07g27970 No alias O-methyltransferase, putative, expressed 0.02 Orthogroups_2024-Update
PSME_00006686-RA No alias (q9fqy8|comt1_capan : 349.0) Caffeic acid... 0.05 Orthogroups_2024-Update
PSME_00008876-RA No alias (p93324|chomt_medsa : 161.0) Isoliquiritigenin... 0.04 Orthogroups_2024-Update
PSME_00008877-RA No alias (q8w013|comt1_catro : 225.0) Caffeic acid... 0.04 Orthogroups_2024-Update
PSME_00023722-RA No alias (p28002|comt1_medsa : 233.0) Caffeic acid... 0.04 Orthogroups_2024-Update
PSME_00037662-RA No alias (q8w013|comt1_catro : 274.0) Caffeic acid... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008171 O-methyltransferase activity IEA InterProScan predictions
MF GO:0046983 protein dimerization activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
BP GO:0006855 drug transmembrane transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
CC GO:0016459 myosin complex IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016840 carbon-nitrogen lyase activity IEP Predicted GO
MF GO:0016843 amine-lyase activity IEP Predicted GO
MF GO:0016844 strictosidine synthase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0044430 cytoskeletal part IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001077 O_MeTrfase_2 137 339
IPR012967 Plant_MeTrfase_dimerisation 32 81
No external refs found!