PSME_00038106-RA


Description : (at5g58230 : 182.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 364.0) & (original description: no original description)


Gene families : OG_42_0127753 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00038106-RA
Cluster HCCA clusters: Cluster_202


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEP Predicted GO
MF GO:0016636 oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0022804 active transmembrane transporter activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
MF GO:0051743 red chlorophyll catabolite reductase activity IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
InterPro domains Description Start Stop
IPR007123 Gelsolin-like_dom 6 39
IPR001680 WD40_repeat 88 117
IPR001680 WD40_repeat 51 81
IPR001680 WD40_repeat 159 194
No external refs found!