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- Pseudotsuga menziesii
- Sequence
- PSME_00038106-RA
PSME_00038106-RA
Description : (at5g58230 : 182.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 364.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Pseudotsuga release: PSME_00038106-RA | |
Cluster | HCCA clusters: Cluster_202 | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0005488 | binding | None | Extended |
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
MF | GO:0008144 | drug binding | IEP | Predicted GO |
MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | IEP | Predicted GO |
MF | GO:0016636 | oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor | IEP | Predicted GO |
MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
MF | GO:0042623 | ATPase activity, coupled | IEP | Predicted GO |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
MF | GO:0051743 | red chlorophyll catabolite reductase activity | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |