PSME_00040762-RA


Description : (at2g41500 : 516.0) Encodes LACHESIS (LIS), a protein with seven WD40 repeats. LIS is homologous to the yeast splicing factor PRP4 which is associated with the U4/U6 complex of the spliceosome. LIS is involved in a mechanism that prevents accessory cells from adopting gametic cell fate: lis mutant forms supernumerary egg cells.; LACHESIS (LIS); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), Pre-mRNA processing factor 4 (PRP4) like (InterPro:IPR014906), WD40 repeat (InterPro:IPR001680), Splicing factor motif (InterPro:IPR003648), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT2G05720.1); Has 96331 Blast hits to 36444 proteins in 930 species: Archae - 78; Bacteria - 11869; Metazoa - 38307; Fungi - 21059; Plants - 12275; Viruses - 15; Other Eukaryotes - 12728 (source: NCBI BLink). & (p93107|pf20_chlre : 107.0) Flagellar WD repeat protein PF20 - Chlamydomonas reinhardtii & (reliability: 1032.0) & (original description: no original description)


Gene families : OG_42_0004189 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004189_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00040762-RA
Cluster HCCA clusters: Cluster_126

Target Alias Description ECC score Gene Family Method Actions
HORVU4Hr1G034750.1 No alias component *(PRPF4) of spliceosomal U4/U6 snRNP 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEP Predicted GO
BP GO:0000956 nuclear-transcribed mRNA catabolic process IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0004652 polynucleotide adenylyltransferase activity IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006401 RNA catabolic process IEP Predicted GO
BP GO:0006402 mRNA catabolic process IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
BP GO:0009892 negative regulation of metabolic process IEP Predicted GO
BP GO:0010605 negative regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010629 negative regulation of gene expression IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016071 mRNA metabolic process IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
BP GO:0043085 positive regulation of catalytic activity IEP Predicted GO
BP GO:0043631 RNA polyadenylation IEP Predicted GO
BP GO:0044093 positive regulation of molecular function IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
BP GO:0050790 regulation of catalytic activity IEP Predicted GO
BP GO:0065009 regulation of molecular function IEP Predicted GO
MF GO:0070566 adenylyltransferase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR014906 PRP4-like 263 291
IPR001680 WD40_repeat 473 509
IPR001680 WD40_repeat 560 593
IPR001680 WD40_repeat 431 468
IPR001680 WD40_repeat 520 551
No external refs found!