Description : (at1g68890 : 290.0) Homologous to the four eubacterial men genes involved in menanoquinone biosynthesis. Studies of mutants defective in this gene demonstrated its involvement in phylloquinone biosynthesis in Arabidopsis.; magnesium ion binding;thiamin pyrophosphate binding;hydro-lyases;catalytics;2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthases; FUNCTIONS IN: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity, hydro-lyase activity, magnesium ion binding, thiamin pyrophosphate binding, catalytic activity; INVOLVED IN: phylloquinone biosynthetic process, photosystem I stabilization; LOCATED IN: chloroplast; EXPRESSED IN: shoot, leaf whorl; CONTAINS InterPro DOMAIN/s: Menaquinone biosynthesis protein MenD (InterPro:IPR004433), Alpha/beta hydrolase fold-1 (InterPro:IPR000073), Mandelate racemase/muconate lactonizing enzyme, C-terminal (InterPro:IPR013342), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), O-succinylbenzoic acid (OSB) synthetase, gamma proteobacteria/archaea (InterPro:IPR010196), Mandelate racemase/muconate lactonizing enzyme, conserved site (InterPro:IPR018110); BEST Arabidopsis thaliana protein match is: isochorismate synthase 2 (TAIR:AT1G18870.2); Has 22452 Blast hits to 22188 proteins in 2448 species: Archae - 403; Bacteria - 16894; Metazoa - 237; Fungi - 200; Plants - 484; Viruses - 7; Other Eukaryotes - 4227 (source: NCBI BLink). & (reliability: 580.0) & (original description: no original description)
Gene families : OG_42_0004468 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004468_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00041579-RA | |
Cluster | HCCA clusters: Cluster_206 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Cre16.g659050 | No alias | magnesium ion binding;thiamin pyrophosphate... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004089 | carbonate dehydratase activity | IEP | Predicted GO |
MF | GO:0004559 | alpha-mannosidase activity | IEP | Predicted GO |
MF | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | IEP | Predicted GO |
MF | GO:0004853 | uroporphyrinogen decarboxylase activity | IEP | Predicted GO |
BP | GO:0006188 | IMP biosynthetic process | IEP | Predicted GO |
BP | GO:0006189 | 'de novo' IMP biosynthetic process | IEP | Predicted GO |
BP | GO:0006281 | DNA repair | IEP | Predicted GO |
BP | GO:0006778 | porphyrin-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006779 | porphyrin-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
CC | GO:0009507 | chloroplast | IEP | Predicted GO |
CC | GO:0009536 | plastid | IEP | Predicted GO |
MF | GO:0015923 | mannosidase activity | IEP | Predicted GO |
MF | GO:0015924 | mannosyl-oligosaccharide mannosidase activity | IEP | Predicted GO |
MF | GO:0016829 | lyase activity | IEP | Predicted GO |
MF | GO:0016835 | carbon-oxygen lyase activity | IEP | Predicted GO |
MF | GO:0016836 | hydro-lyase activity | IEP | Predicted GO |
BP | GO:0033013 | tetrapyrrole metabolic process | IEP | Predicted GO |
BP | GO:0033014 | tetrapyrrole biosynthetic process | IEP | Predicted GO |
BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
BP | GO:0046040 | IMP metabolic process | IEP | Predicted GO |
BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000073 | AB_hydrolase_1 | 213 | 347 |
No external refs found! |