PSME_00041857-RA


Description : (p31251|ube12_wheat : 1366.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at5g06460 : 1355.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined.; ubiquitin activating enzyme 2 (UBA 2); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin-activating enzyme 1 (TAIR:AT2G30110.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 2710.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00041857-RA
Cluster HCCA clusters: Cluster_230

Target Alias Description ECC score Gene Family Method Actions
Brara.E01311.1 No alias E1 ubiquitin-activating enzyme 0.03 Orthogroups_2024-Update
Kfl00533_0100 kfl00533_0100_v1.1 (p31251|ube12_wheat : 672.0) Ubiquitin-activating enzyme... 0.02 Orthogroups_2024-Update
MA_10436331g0040 No alias (at2g30110 : 1273.0) Encodes a ubiquitin-activating... 0.02 Orthogroups_2024-Update
PSME_00016231-RA No alias (p31251|ube12_wheat : 1320.0) Ubiquitin-activating... 0.05 Orthogroups_2024-Update
Sopen06g002240 No alias ThiF family 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003909 DNA ligase activity IEP Predicted GO
MF GO:0003910 DNA ligase (ATP) activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005244 voltage-gated ion channel activity IEP Predicted GO
MF GO:0005247 voltage-gated chloride channel activity IEP Predicted GO
MF GO:0005253 anion channel activity IEP Predicted GO
MF GO:0005254 chloride channel activity IEP Predicted GO
BP GO:0006310 DNA recombination IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006811 ion transport IEP Predicted GO
BP GO:0006821 chloride transport IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
MF GO:0008308 voltage-gated anion channel activity IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015108 chloride transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0016851 magnesium chelatase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016886 ligase activity, forming phosphoric ester bonds IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022832 voltage-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
MF GO:0030695 GTPase regulator activity IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0051002 ligase activity, forming nitrogen-metal bonds IEP Predicted GO
MF GO:0051003 ligase activity, forming nitrogen-metal bonds, forming coordination complexes IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
InterPro domains Description Start Stop
IPR018965 Ub-activating_enz_E1_C 950 1025
IPR000594 ThiF_NAD_FAD-bd 437 938
IPR019572 UBA_E1_Cys 625 880
IPR032418 E1_FCCH 207 280
IPR032420 E1_4HB 281 350
IPR000594 ThiF_NAD_FAD-bd 33 422
No external refs found!