Description : (at2g13560 : 253.0) Encodes an NAD-dependent malic enzyme (NAD-ME) that does not act on oxaloacetate, indicating that it belongs to EC 1.1.1.39. It is a member of the alpha family of NAD-MEs in plants. It appears to function as a homodimer or as a heterodimer with the beta-type NAD-ME2 (At4g00570). NAD-ME1 transcript and protein levels are higher during the night than during the day.; NAD-dependent malic enzyme 1 (NAD-ME1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to salt stress, malate metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD-dependent malic enzyme 2 (TAIR:AT4G00570.1); Has 9465 Blast hits to 9448 proteins in 2440 species: Archae - 143; Bacteria - 6328; Metazoa - 607; Fungi - 221; Plants - 457; Viruses - 0; Other Eukaryotes - 1709 (source: NCBI BLink). & (p37221|maom_soltu : 246.0) NAD-dependent malic enzyme 62 kDa isoform, mitochondrial precursor (EC 1.1.1.39) (NAD-ME) - Solanum tuberosum (Potato) & (reliability: 506.0) & (original description: no original description)
Gene families : OG_42_0013286 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0013286_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00042061-RA | |
Cluster | HCCA clusters: Cluster_72 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004471 | malate dehydrogenase (decarboxylating) (NAD+) activity | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003872 | 6-phosphofructokinase activity | IEP | Predicted GO |
BP | GO:0006090 | pyruvate metabolic process | IEP | Predicted GO |
BP | GO:0006096 | glycolytic process | IEP | Predicted GO |
BP | GO:0006165 | nucleoside diphosphate phosphorylation | IEP | Predicted GO |
BP | GO:0006694 | steroid biosynthetic process | IEP | Predicted GO |
BP | GO:0006757 | ATP generation from ADP | IEP | Predicted GO |
BP | GO:0008202 | steroid metabolic process | IEP | Predicted GO |
MF | GO:0008443 | phosphofructokinase activity | IEP | Predicted GO |
BP | GO:0009132 | nucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009135 | purine nucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009166 | nucleotide catabolic process | IEP | Predicted GO |
BP | GO:0009179 | purine ribonucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009185 | ribonucleoside diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0016226 | iron-sulfur cluster assembly | IEP | Predicted GO |
MF | GO:0019200 | carbohydrate kinase activity | IEP | Predicted GO |
BP | GO:0019359 | nicotinamide nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0019362 | pyridine nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0019363 | pyridine nucleotide biosynthetic process | IEP | Predicted GO |
CC | GO:0030117 | membrane coat | IEP | Predicted GO |
BP | GO:0031163 | metallo-sulfur cluster assembly | IEP | Predicted GO |
MF | GO:0033926 | glycopeptide alpha-N-acetylgalactosaminidase activity | IEP | Predicted GO |
BP | GO:0042866 | pyruvate biosynthetic process | IEP | Predicted GO |
BP | GO:0046031 | ADP metabolic process | IEP | Predicted GO |
BP | GO:0046496 | nicotinamide nucleotide metabolic process | IEP | Predicted GO |
MF | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | IEP | Predicted GO |
BP | GO:0046939 | nucleotide phosphorylation | IEP | Predicted GO |
BP | GO:0051186 | cofactor metabolic process | IEP | Predicted GO |
MF | GO:0051536 | iron-sulfur cluster binding | IEP | Predicted GO |
MF | GO:0051537 | 2 iron, 2 sulfur cluster binding | IEP | Predicted GO |
MF | GO:0051540 | metal cluster binding | IEP | Predicted GO |
BP | GO:0072525 | pyridine-containing compound biosynthetic process | IEP | Predicted GO |
MF | GO:0140103 | catalytic activity, acting on a glycoprotein | IEP | Predicted GO |
BP | GO:1901292 | nucleoside phosphate catabolic process | IEP | Predicted GO |
BP | GO:1901362 | organic cyclic compound biosynthetic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR012301 | Malic_N_dom | 32 | 142 |
No external refs found! |