PSME_00043235-RA


Description : (at1g48050 : 112.0) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 224.0) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00043235-RA
Cluster HCCA clusters: Cluster_271

Target Alias Description ECC score Gene Family Method Actions
PSME_00033536-RA No alias (at1g48050 : 111.0) Ku80 and ku70 form the heterodimer... 0.05 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003950 NAD+ ADP-ribosyltransferase activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
CC GO:0005576 extracellular region IEP Predicted GO
CC GO:0005618 cell wall IEP Predicted GO
BP GO:0005976 polysaccharide metabolic process IEP Predicted GO
BP GO:0006606 protein import into nucleus IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0010333 terpene synthase activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0016762 xyloglucan:xyloglucosyl transferase activity IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Predicted GO
MF GO:0016846 carbon-sulfur lyase activity IEP Predicted GO
BP GO:0017038 protein import IEP Predicted GO
CC GO:0030312 external encapsulating structure IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034504 protein localization to nucleus IEP Predicted GO
BP GO:0034613 cellular protein localization IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
CC GO:0048046 apoplast IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051170 import into nucleus IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
MF GO:0061608 nuclear import signal receptor activity IEP Predicted GO
BP GO:0070727 cellular macromolecule localization IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
MF GO:0140142 nucleocytoplasmic carrier activity IEP Predicted GO
InterPro domains Description Start Stop
IPR014893 Ku_PK_bind 137 192
No external refs found!