PSME_00043612-RA

Description : (at2g47800 : 249.0) Encodes a plasma membrane localized ATPase transporter involved in multidrug transport. The expression of this gene is upregulated by herbicide safeners such as benoxacor, fluxofenim and fenclorim.; multidrug resistance-associated protein 4 (MRP4); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, folic acid transporter activity; INVOLVED IN: response to water deprivation, drug transmembrane transport, response to wounding, response to nematode, stomatal movement; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 10 (TAIR:AT3G62700.1); Has 714857 Blast hits to 368077 proteins in 3991 species: Archae - 12925; Bacteria - 579268; Metazoa - 12980; Fungi - 8565; Plants - 6599; Viruses - 19; Other Eukaryotes - 94501 (source: NCBI BLink). & (reliability: 498.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pseudotsuga release: PSME_00043612-RA
Cluster	HCCA clusters: Cluster_240

Target	Alias	Description	ECC score	Gene Family Method
Brara.K00933.1	No alias	Unknown function	0.04	Orthogroups_2024-Update
MA_629244g0010	No alias	(at3g62700 : 457.0) member of MRP subfamily; multidrug...	0.03	Orthogroups_2024-Update
Potri.001G362300	No alias	multidrug resistance-associated protein 3	0.03	Orthogroups_2024-Update
Potri.002G205500	No alias	multidrug resistance-associated protein 4	0.02	Orthogroups_2024-Update
Sobic.001G491200.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Sobic.003G160200.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Sobic.007G210500.2	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Solyc10g024420	No alias	ABC transporter family protein (AHRD V3.3 *** B9IB53_POPTR)	0.03	Orthogroups_2024-Update
Sopen08g002840	No alias	ABC transporter transmembrane region	0.03	Orthogroups_2024-Update
Sopen09g029840	No alias	ABC transporter transmembrane region	0.04	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
MF	GO:0008144	drug binding	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004568	chitinase activity	IEP	Predicted GO
MF	GO:0005516	calmodulin binding	IEP	Predicted GO
BP	GO:0005996	monosaccharide metabolic process	IEP	Predicted GO
BP	GO:0006006	glucose metabolic process	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006026	aminoglycan catabolic process	IEP	Predicted GO
BP	GO:0006030	chitin metabolic process	IEP	Predicted GO
BP	GO:0006032	chitin catabolic process	IEP	Predicted GO
BP	GO:0006040	amino sugar metabolic process	IEP	Predicted GO
BP	GO:0006359	regulation of transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
MF	GO:0009916	alternative oxidase activity	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010629	negative regulation of gene expression	IEP	Predicted GO
BP	GO:0016125	sterol metabolic process	IEP	Predicted GO
BP	GO:0016480	negative regulation of transcription by RNA polymerase III	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Predicted GO
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	IEP	Predicted GO
BP	GO:0016998	cell wall macromolecule catabolic process	IEP	Predicted GO
BP	GO:0019318	hexose metabolic process	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0042737	drug catabolic process	IEP	Predicted GO
BP	GO:0044036	cell wall macromolecule metabolic process	IEP	Predicted GO
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0046348	amino sugar catabolic process	IEP	Predicted GO
MF	GO:0047750	cholestenol delta-isomerase activity	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:1901071	glucosamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901072	glucosamine-containing compound catabolic process	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	85	120

External Links

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PSME_00043612-RA

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation