PSME_00044237-RA


Description : (at5g41360 : 583.0) Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.; homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1166.0) & (original description: no original description)


Gene families : OG_42_0003616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003616_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00044237-RA
Cluster HCCA clusters: Cluster_41

Target Alias Description ECC score Gene Family Method Actions
Brara.D01141.1 No alias component *(SSL2/XPB) of TFIIh basal transcription... 0.02 Orthogroups_2024-Update
evm.model.contig_3597.6 No alias (at5g41360 : 736.0) Encodes XPB2, a DNA repair protein... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
MF GO:0016787 hydrolase activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEP Predicted GO
MF GO:0004144 diacylglycerol O-acyltransferase activity IEP Predicted GO
MF GO:0008374 O-acyltransferase activity IEP Predicted GO
MF GO:0010333 terpene synthase activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0016411 acylglycerol O-acyltransferase activity IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016838 carbon-oxygen lyase activity, acting on phosphates IEP Predicted GO
MF GO:0016872 intramolecular lyase activity IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
InterPro domains Description Start Stop
IPR032438 ERCC3_RAD25_C 385 625
IPR006935 Helicase/UvrB_N 202 359
IPR032830 XPB/Ssl2_N 26 149
No external refs found!