Description : (at1g08260 : 150.0) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 300.0) & (original description: no original description)
Gene families : OG_42_0002789 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002789_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pseudotsuga release: PSME_00044359-RA | |
Cluster | HCCA clusters: Cluster_7 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000278 | mitotic cell cycle | IEP | Predicted GO |
CC | GO:0000775 | chromosome, centromeric region | IEP | Predicted GO |
MF | GO:0004089 | carbonate dehydratase activity | IEP | Predicted GO |
MF | GO:0004618 | phosphoglycerate kinase activity | IEP | Predicted GO |
MF | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity | IEP | Predicted GO |
CC | GO:0005779 | integral component of peroxisomal membrane | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006163 | purine nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0006164 | purine nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0006396 | RNA processing | IEP | Predicted GO |
BP | GO:0006399 | tRNA metabolic process | IEP | Predicted GO |
BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
BP | GO:0006753 | nucleoside phosphate metabolic process | IEP | Predicted GO |
BP | GO:0006754 | ATP biosynthetic process | IEP | Predicted GO |
BP | GO:0007049 | cell cycle | IEP | Predicted GO |
BP | GO:0008033 | tRNA processing | IEP | Predicted GO |
MF | GO:0008170 | N-methyltransferase activity | IEP | Predicted GO |
MF | GO:0008173 | RNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0008175 | tRNA methyltransferase activity | IEP | Predicted GO |
MF | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | IEP | Predicted GO |
BP | GO:0009117 | nucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009123 | nucleoside monophosphate metabolic process | IEP | Predicted GO |
BP | GO:0009124 | nucleoside monophosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009126 | purine nucleoside monophosphate metabolic process | IEP | Predicted GO |
BP | GO:0009127 | purine nucleoside monophosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009141 | nucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009142 | nucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009144 | purine nucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009145 | purine nucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009150 | purine ribonucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009152 | purine ribonucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0009156 | ribonucleoside monophosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009161 | ribonucleoside monophosphate metabolic process | IEP | Predicted GO |
BP | GO:0009165 | nucleotide biosynthetic process | IEP | Predicted GO |
BP | GO:0009167 | purine ribonucleoside monophosphate metabolic process | IEP | Predicted GO |
BP | GO:0009168 | purine ribonucleoside monophosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009199 | ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009201 | ribonucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009205 | purine ribonucleoside triphosphate metabolic process | IEP | Predicted GO |
BP | GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0009259 | ribonucleotide metabolic process | IEP | Predicted GO |
BP | GO:0009260 | ribonucleotide biosynthetic process | IEP | Predicted GO |
MF | GO:0015267 | channel activity | IEP | Predicted GO |
BP | GO:0015985 | energy coupled proton transport, down electrochemical gradient | IEP | Predicted GO |
BP | GO:0015986 | ATP synthesis coupled proton transport | IEP | Predicted GO |
MF | GO:0016423 | tRNA (guanine) methyltransferase activity | IEP | Predicted GO |
BP | GO:0016559 | peroxisome fission | IEP | Predicted GO |
MF | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor | IEP | Predicted GO |
MF | GO:0016836 | hydro-lyase activity | IEP | Predicted GO |
BP | GO:0017144 | drug metabolic process | IEP | Predicted GO |
BP | GO:0018130 | heterocycle biosynthetic process | IEP | Predicted GO |
BP | GO:0019637 | organophosphate metabolic process | IEP | Predicted GO |
BP | GO:0019693 | ribose phosphate metabolic process | IEP | Predicted GO |
MF | GO:0019829 | cation-transporting ATPase activity | IEP | Predicted GO |
MF | GO:0022803 | passive transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0022853 | active ion transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0031231 | intrinsic component of peroxisomal membrane | IEP | Predicted GO |
CC | GO:0031300 | intrinsic component of organelle membrane | IEP | Predicted GO |
CC | GO:0031301 | integral component of organelle membrane | IEP | Predicted GO |
BP | GO:0034470 | ncRNA processing | IEP | Predicted GO |
BP | GO:0034654 | nucleobase-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0034660 | ncRNA metabolic process | IEP | Predicted GO |
MF | GO:0042625 | ATPase coupled ion transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0044438 | microbody part | IEP | Predicted GO |
CC | GO:0044439 | peroxisomal part | IEP | Predicted GO |
MF | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism | IEP | Predicted GO |
BP | GO:0046034 | ATP metabolic process | IEP | Predicted GO |
BP | GO:0046390 | ribose phosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
MF | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism | IEP | Predicted GO |
BP | GO:0048285 | organelle fission | IEP | Predicted GO |
BP | GO:0055086 | nucleobase-containing small molecule metabolic process | IEP | Predicted GO |
BP | GO:0072521 | purine-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0072522 | purine-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0090407 | organophosphate biosynthetic process | IEP | Predicted GO |
CC | GO:0098687 | chromosomal region | IEP | Predicted GO |
MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
BP | GO:1901135 | carbohydrate derivative metabolic process | IEP | Predicted GO |
BP | GO:1901137 | carbohydrate derivative biosynthetic process | IEP | Predicted GO |
BP | GO:1901293 | nucleoside phosphate biosynthetic process | IEP | Predicted GO |
BP | GO:1901360 | organic cyclic compound metabolic process | IEP | Predicted GO |
No external refs found! |