PSME_00045960-RA


Description : (at3g24495 : 245.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (q9xj60|mad50_orysa : 105.0) MADS-box transcription factor 50 (OsMADS50) (Protein SUPPRESSOR OF CONSTANS OVEREXPRESSION 1-like) (OsSOC1) (Protein AGAMOUS-like 20) (RMADS208) - Oryza sativa (Rice) & (reliability: 490.0) & (original description: no original description)


Gene families : OG_42_0001047 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001047_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00045960-RA
Cluster HCCA clusters: Cluster_237

Target Alias Description ECC score Gene Family Method Actions
Kfl00266_0120 kfl00266_0120_v1.1 (at3g24495 : 377.0) encodes a DNA mismatch repair... 0.03 Orthogroups_2024-Update
evm.model.tig00000489.16 No alias (at4g02070 : 188.0) encodes a DNA mismatch repair... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006298 mismatch repair IEA InterProScan predictions
MF GO:0030983 mismatched DNA binding IEA InterProScan predictions
MF GO:0046983 protein dimerization activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0005048 signal sequence binding IEP Predicted GO
BP GO:0006621 protein retention in ER lumen IEP Predicted GO
BP GO:0006644 phospholipid metabolic process IEP Predicted GO
BP GO:0006650 glycerophospholipid metabolic process IEP Predicted GO
MF GO:0016307 phosphatidylinositol phosphate kinase activity IEP Predicted GO
BP GO:0032507 maintenance of protein location in cell IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
BP GO:0035437 maintenance of protein localization in endoplasmic reticulum IEP Predicted GO
MF GO:0042277 peptide binding IEP Predicted GO
BP GO:0045185 maintenance of protein location IEP Predicted GO
BP GO:0046486 glycerolipid metabolic process IEP Predicted GO
BP GO:0046488 phosphatidylinositol metabolic process IEP Predicted GO
MF GO:0046923 ER retention sequence binding IEP Predicted GO
BP GO:0051235 maintenance of location IEP Predicted GO
BP GO:0051651 maintenance of location in cell IEP Predicted GO
BP GO:0072595 maintenance of protein localization in organelle IEP Predicted GO
InterPro domains Description Start Stop
IPR000432 DNA_mismatch_repair_MutS_C 359 467
IPR002100 TF_MADSbox 10 58
No external refs found!