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  5. PSME_00047362-RA

PSME_00047362-RA


Description : (at1g48050 : 157.0) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 314.0) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00047362-RA
Cluster HCCA clusters: Cluster_195


Type GO Term Name Evidence Source
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEA InterProScan predictions
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Type GO Term Name Evidence Source
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005759 mitochondrial matrix IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0008156 negative regulation of DNA replication IEP Predicted GO
CC GO:0009521 photosystem IEP Predicted GO
CC GO:0009523 photosystem II IEP Predicted GO
CC GO:0009539 photosystem II reaction center IEP Predicted GO
BP GO:0009890 negative regulation of biosynthetic process IEP Predicted GO
BP GO:0009892 negative regulation of metabolic process IEP Predicted GO
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010605 negative regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0015979 photosynthesis IEP Predicted GO
BP GO:0031324 negative regulation of cellular metabolic process IEP Predicted GO
BP GO:0031327 negative regulation of cellular biosynthetic process IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
CC GO:0031974 membrane-enclosed lumen IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
CC GO:0043233 organelle lumen IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044429 mitochondrial part IEP Predicted GO
CC GO:0044436 thylakoid part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045005 DNA-dependent DNA replication maintenance of fidelity IEP Predicted GO
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0048478 replication fork protection IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
BP GO:0048523 negative regulation of cellular process IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051053 negative regulation of DNA metabolic process IEP Predicted GO
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Predicted GO
CC GO:0070013 intracellular organelle lumen IEP Predicted GO
MF GO:0071949 FAD binding IEP Predicted GO
BP GO:0090329 regulation of DNA-dependent DNA replication IEP Predicted GO
BP GO:2000104 negative regulation of DNA-dependent DNA replication IEP Predicted GO
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR014893 Ku_PK_bind 96 211
No external refs found!