PSME_00047653-RA


Description : (q41438|hmdh3_soltu : 751.0) 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3 (EC 1.1.1.34) (HMG-CoA reductase 3) (HMG3.3) - Solanum tuberosum (Potato) & (at1g76490 : 728.0) Encodes a 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in melavonate biosynthesis and performs the first committed step in isoprenoid biosynthesis. Expression is activated in dark in leaf tissue but not controlled by light in the root (confine; hydroxy methylglutaryl CoA reductase 1 (HMG1); CONTAINS InterPro DOMAIN/s: Hydroxymethylglutaryl-CoA reductase, class I, catalytic (InterPro:IPR004554), Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding (InterPro:IPR009029), Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding (InterPro:IPR009023), Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic (InterPro:IPR002202); BEST Arabidopsis thaliana protein match is: 3-hydroxy-3-methylglutaryl-CoA reductase 2 (TAIR:AT2G17370.1); Has 2212 Blast hits to 2210 proteins in 935 species: Archae - 202; Bacteria - 1018; Metazoa - 225; Fungi - 225; Plants - 266; Viruses - 1; Other Eukaryotes - 275 (source: NCBI BLink). & (reliability: 1456.0) & (original description: no original description)


Gene families : OG_42_0129477 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00047653-RA
Cluster HCCA clusters: Cluster_137


Type GO Term Name Evidence Source
MF GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IEA InterProScan predictions
BP GO:0015936 coenzyme A metabolic process IEA InterProScan predictions
MF GO:0050662 coenzyme binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003682 chromatin binding IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
MF GO:0046872 metal ion binding IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
InterPro domains Description Start Stop
IPR002202 HMG_CoA_Rdtase 161 544
No external refs found!