PSME_00049001-RA


Description : (at5g57090 : 117.0) Encodes an auxin efflux carrier that is similar to bacterial membrane transporters. Root-specific role in the transport of auxin. Acts downstream of CTR1 and ethylene biosynthesis, in the same pathway as EIN2 and AUX1, and independent from EIN3 and EIN5/AIN1 pathway. In the root, the protein localizes apically in epidermal and lateral root cap cells and predominantly basally in cortical cells. Functions may be regulated by phosphorylation status. EIR1 expression is induced by brassinolide treatment in the brassinosteroid-insensitive br1 mutant. Gravistimulation resulted in asymmetric PIN2 distribution, with more protein degraded at the upper side of the gravistimulated root. Protein turnover is affected by the proteasome and by endosomal cycling. Plasma membrane-localized PIN proteins mediate a saturable efflux of auxin. PINs mediate auxin efflux from mammalian and yeast cells without needing additional plant-specific factors. The action of PINs in auxin efflux is distinct from PGPs, rate-limiting, specific to auxins and sensitive to auxin transport inhibitors. Membrane sterol composition is essential for the acquisition of PIN2 polarity.; ETHYLENE INSENSITIVE ROOT 1 (EIR1); CONTAINS InterPro DOMAIN/s: Auxin efflux carrier, subgroup (InterPro:IPR014024), Auxin efflux carrier (InterPro:IPR004776); BEST Arabidopsis thaliana protein match is: Auxin efflux carrier family protein (TAIR:AT2G01420.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q651v6|pin2_orysa : 114.0) Probable auxin efflux carrier component 2 (OsPIN2) - Oryza sativa (Rice) & (reliability: 234.0) & (original description: no original description)


Gene families : OG_42_0000235 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000235_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pseudotsuga release: PSME_00049001-RA

Target Alias Description ECC score Gene Family Method Actions
Brara.G03257.1 No alias auxin transporter *(PIN) & auxin efflux transporter *(PIN) 0.02 Orthogroups_2024-Update
Glyma.07G217900 No alias Auxin efflux carrier family protein 0.02 Orthogroups_2024-Update
PSME_00020548-RA No alias (at5g57090 : 686.0) Encodes an auxin efflux carrier that... 0.05 Orthogroups_2024-Update
Potri.005G187500 No alias Auxin efflux carrier family protein 0.04 Orthogroups_2024-Update
Solyc05g008060 No alias SlPIN4 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0016021 integral component of membrane IEA InterProScan predictions
BP GO:0055085 transmembrane transport IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
MF GO:0033897 ribonuclease T2 activity IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR004776 Mem_trans 71 101
IPR004776 Mem_trans 1 66
No external refs found!